Lamisil

Terbinafine Hydrochloride, the active ingredient in Lamisil, is a allylamine antifungal presented as a topical formulation for skin application. It treats fungal infections of the skin and nails, such as athlete's foot, ringworm, jock itch, and onychomycosis, in adult and pediatric patients as directed by a healthcare professional.

GNH USA supplies Lamisil as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Lamisil (terbinafine) acts on dermatophyte fungi that cause superficial skin and nail infections. - Tinea pedis: alleviates itching, scaling and redness of athlete's foot. - Tinea corporis: clears ringworm lesions on the body. - Tinea cruris: resolves jock itch symptoms in the groin area. - Onychomycosis: improves fungal nail infection appearance and reduces fungal load.

Topical terbinafine is generally well tolerated, but local and systemic reactions can occur.

Common Side Effects: - Itching: mild to moderate sensation at the application site. - Burning: transient heat sensation after application. - Redness: localized erythema of treated skin. - Dryness or scaling: mild desquamation around the area.

Serious or Rare Side Effects: - Severe allergic reaction: swelling, hives, or anaphylaxis. - Stevens‑Johnson syndrome: rare severe skin blistering. - Hepatotoxicity: abnormal liver enzymes with extensive systemic absorption. - Contact dermatitis: intense irritation or rash. - Systemic toxicity: rare but may include nausea or headache.

Before using Lamisil, consider the following safety measures. - Pregnancy: consult a healthcare professional before use. - Breastfeeding: discuss potential risks with a physician. - Broken skin: avoid application on open wounds or extensive abrasions. - Liver disease: use with caution and monitor liver function if systemic absorption is possible. - Allergy: discontinue if hypersensitivity signs appear. - Store at room temperature: keep below 25 °C in the original container, protected from moisture and light.

Terbinafine may interact with other medications, particularly when systemic absorption occurs.

Major Interactions (Avoid): - Oral terbinafine: concurrent use can increase systemic exposure. - CYP2D6 inhibitors (e.g., fluoxetine): may raise terbinafine levels. - Other topical antifungals: avoid simultaneous application to reduce irritation.

Moderate Interactions (Monitor Closely): - Alcohol: may exacerbate liver enzyme elevations. - Hepatotoxic drugs (e.g., isoniazid): monitor liver function. - Warfarin: observe INR if extensive absorption is suspected.