GNH USA

Europe — EMA

Lamisil

GNH USA supplies Lamisil (Terbinafine Hydrochloride), a allylamine antifungal for athlete's foot, ringworm, jock itch and onychomycosis.

Terbinafine Hydrochloride

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What is Terbinafine Hydrochloride?

Terbinafine Hydrochloride, the active ingredient in Lamisil, is a allylamine antifungal presented as a topical formulation for skin use. It treats fungal infections of the skin, hair, and nails in adults and children as directed by a healthcare professional.

GNH USA supplies Lamisil as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Terbinafine Hydrochloride used for?

Lamisil (terbinafine) is used to treat fungal skin infections caused by dermatophytes.

- Tinea pedis (athlete's foot): reduces itching and clears infection on the feet. - Tinea corporis (ringworm): eliminates the expanding red ring lesions on the body. - Tinea cruris (jock itch): relieves irritation and eradicates the fungus in the groin area. - Tinea unguium (onychomycosis): improves nail appearance by inhibiting fungal growth within the nail plate.

What are the side effects of Terbinafine Hydrochloride?

Lamisil is generally well tolerated, but some users may experience local reactions.

Common Side Effects: - Itching at the application site - Redness or mild rash - Burning or stinging sensation - Dryness or peeling of the skin - Mild irritation or swelling - Scaling or flaking of the treated area

Serious or Rare Side Effects: - Severe allergic reaction (anaphylaxis, angioedema) - Extensive skin rash or blistering (Stevens‑Johnson syndrome) - Swelling of face, lips, or tongue - Difficulty breathing or wheezing - Hepatotoxicity indicated by abnormal liver enzymes - Unusual bruising or bleeding

What precautions apply to Terbinafine Hydrochloride?

Before using Lamisil, consider the following safety measures.

- Pregnancy: consult a healthcare provider before application. - Breastfeeding: discuss potential risks with a doctor. - Apply only to intact, non‑broken skin. - Avoid extensive use on large body areas without medical advice. - Do not apply to mucous membranes, eyes, or genital mucosa. - Store at room temperature: keep in the original container, protect from moisture and light.

What does Terbinafine Hydrochloride interact with?

Terbinafine may interact with other medications; monitor for combined effects.

Major Interactions (Avoid): - Systemic azoles (e.g., itraconazole, fluconazole): may increase terbinafine plasma levels. - Strong CYP2D6 inhibitors (e.g., quinidine): can raise systemic exposure.

Moderate Interactions (Monitor Closely): - Topical corticosteroids: may mask local irritation. - Alcohol‑based skin products: could alter absorption. - Other dermatologic agents (e.g., salicylic acid, urea): may increase skin irritation.

Frequently asked questions

What conditions is Lamisil used to treat?+
Lamisil is indicated for the topical treatment of common fungal skin infections such as athlete's foot (tinea pedis), ringworm (tinea corporis), jock itch (tinea cruris), and fungal nail infections (tinea unguium or onychomycosis). It works by targeting the fungus that causes these conditions, helping to relieve symptoms and clear the infection.
How does terbinafine Hydrochloride work?+
Terbinafine Hydrochloride blocks the fungal enzyme squalene epoxidase, which is essential for producing ergosterol, a key component of fungal cell membranes. Inhibiting this step leads to toxic buildup of squalene and loss of membrane integrity, ultimately killing the fungal cells and stopping the infection.
What is the usual dose of Lamisil?+
The specific dosage and frequency of Lamisil are determined by the prescribing healthcare professional based on the infection type, severity, patient age, and treatment area. Patients should follow the prescriber’s instructions and the product label for proper application.
Is Lamisil safe to use during pregnancy or breastfeeding?+
Safety data for topical terbinafine during pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Lamisil.
How do I order Lamisil from GNH USA?+
To place an order, submit an enquiry on the Lamisil product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.
How does Lamisil compare with other antifungal treatments?+
Lamisil belongs to the allylamine class, which differs from azole antifungals that inhibit a later step in ergosterol synthesis. Allylamines like terbinafine often achieve faster fungal clearance and may be preferred for certain dermatophyte infections, though choice depends on infection type, patient factors, and physician judgment.
What are the recommended storage conditions for Lamisil?+
Lamisil should be stored at room temperature, typically below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed when not in use.
How is Lamisil applied?+
Lamisil is applied topically to the affected skin area. Clean and dry the area before use, then spread a thin layer of the cream or gel as directed by the prescriber, usually once or twice daily. Wash hands after application unless the hands are the treatment site.
What are the most serious risks associated with Lamisil?+
While rare, serious adverse reactions can include severe allergic responses such as anaphylaxis, extensive skin rashes like Stevens‑Johnson syndrome, and liver toxicity indicated by abnormal liver function tests. Patients should seek immediate medical attention if they notice signs of a serious reaction.
Who should not use Lamisil?+
Lamisil should not be used on broken or inflamed skin, on mucous membranes, or by individuals with a known hypersensitivity to terbinafine or any component of the formulation. Patients with severe liver disease should also avoid use unless specifically advised by a physician.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Terbinafine Hydrochloride
Route
Cutaneous Use
Manufacturer
Karo Healthcare Ab
Origin
EU

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