Lamisil

Terbinafine Hydrochloride, the active ingredient in Lamisil, is an allylamine antifungal presented as a topical cream for cutaneous use. It treats fungal skin infections such as athlete’s foot, ringworm, jock itch and nail fungus in adults and children.

GNH USA supplies Lamisil as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Terbinafine is an allylamine antifungal used to treat dermatophyte infections of the skin and nails.

- Athlete’s foot (tinea pedis): reduces fungal growth and alleviates itching and scaling. - Ringworm (tinea corporis): clears skin lesions caused by dermatophytes. - Jock itch (tinea cruris): eliminates infection and relieves discomfort. - Nail fungus (onychomycosis): improves nail appearance and eradicates fungal colonisation.

Terbinafine cream may cause local and systemic reactions.

Common Side Effects: - Application site irritation: redness, burning or itching at the site of use. - Dryness: mild skin dryness where applied. - Pruritus: transient itching.

Serious or Rare Side Effects: - Severe allergic reaction: rash, swelling, or difficulty breathing. - Contact dermatitis: intense skin inflammation. - Systemic absorption leading to liver enzyme elevation (rare with extensive use).

Before using Lamisil cream, consider the following precautions.

- Pregnancy: consult a healthcare provider before use. - Breastfeeding: avoid application on broken skin and discuss with a physician. - Age: safety not established in children under 2 years. - Concurrent liver disease: monitor liver function if extensive application is required. - Avoid use on extensive broken skin or mucous membranes. - Store at room temperature: keep in the original container, protect from moisture and light.

Terbinafine may interact with other medicines; review the following.

Major Interactions (Avoid): - CYP2D6 inhibitors: may increase systemic terbinafine levels when absorbed. - Rifampin: may reduce terbinafine efficacy by inducing metabolism.

Moderate Interactions (Monitor Closely): - Oral antifungals (itraconazole, fluconazole): concurrent use may increase risk of hepatotoxicity. - Alcohol: may exacerbate liver effects. - Topical corticosteroids: may alter absorption and efficacy.