GNH USA

Europe — EMA

Lamisil Once

GNH USA supplies Lamisil Once (Terbinafine), an antifungal for athlete's foot, ringworm and jock itch. Request a quote for global supply to meet your needs.

Terbinafine

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1
Pack/s

What is Terbinafine?

Terbinafine, the active ingredient in Lamisil Once, is a allylamine antifungal presented as a 1% cream for topical use. It treats fungal skin infections such as athlete's foot, ringworm and jock itch in adults and children.

GNH USA supplies Lamisil Once as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Terbinafine used for?

Terbinafine is an allylamine antifungal used to treat superficial dermatophyte infections.

- Tinea pedis: alleviates itching and clears fungal infection of the feet. - Tinea corporis: resolves ring-shaped skin lesions caused by dermatophytes. - Tinea cruris: treats fungal infection of the groin area, reducing redness and scaling.

What are the side effects of Terbinafine?

Topical terbinafine may cause local skin reactions and, rarely, systemic adverse events.

Common Side Effects: - Burning sensation: mild burning at the application site. - Itching: localized itching or pruritus. - Redness: erythema of the treated skin. - Dryness: skin dryness or flaking.

Serious or Rare Side Effects: - Allergic reaction: rash, swelling, or hives indicating hypersensitivity. - Contact dermatitis: severe irritation or eczema at the site. - Hepatotoxicity: rare liver enzyme elevations. - Stevens-Johnson syndrome: extremely rare severe skin reaction.

What precautions apply to Terbinafine?

When using Lamisil Once, consider the following precautions.

- Apply only to intact skin: avoid broken or inflamed areas. - Avoid ocular or mucosal contact: wash hands after use. - Do not use with other topical antifungals unless directed: risk of irritation. - Discontinue if severe irritation or allergic reaction occurs: seek medical advice. - Store at room temperature: keep in original container, protect from moisture and direct sunlight.

What does Terbinafine interact with?

Terbinafine cream has limited systemic interactions, but certain combinations should be considered.

Major Interactions (Avoid): - Concurrent oral terbinafine: risk of systemic toxicity. - Occlusive dressings: increase absorption leading to systemic side effects.

Moderate Interactions (Monitor Closely): - Other topical antifungals: potential for local irritation. - CYP2D6 inhibitors (e.g., fluoxetine): may affect systemic metabolism if absorbed. - Alcohol: may increase liver strain in rare systemic exposure.

Frequently asked questions

What is Lamisil Once used for?+
Lamisil Once is a 1% terbinafine cream indicated for the topical treatment of superficial fungal skin infections, specifically tinea pedis (athlete's foot), tinea corporis (ringworm), and tinea cruris (jock itch). It helps relieve symptoms such as itching, redness, and scaling while eliminating the underlying dermatophyte infection.
How does terbinafine work?+
Terbinafine belongs to the allylamine class and works by inhibiting the fungal enzyme squalene epoxidase. This blocks the synthesis of ergosterol, an essential component of fungal cell membranes, leading to accumulation of squalene and loss of membrane integrity, which ultimately kills the fungus.
What is the usual dose of Lamisil Once?+
The dosing regimen for Lamisil Once is determined by the prescribing healthcare professional. Typically, a thin layer of the 1% cream is applied once daily to the affected area for a period defined by the clinician, often ranging from one to four weeks depending on the infection.
Is Lamisil Once safe during pregnancy or breastfeeding?+
Safety data for topical terbinafine in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Lamisil Once.
How do I order Lamisil Once from GNH USA?+
To order Lamisil Once, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Lamisil Once compare with other antifungal classes?+
Compared with azole antifungals such as clotrimazole, terbinafine has a different mechanism—blocking squalene epoxidase rather than lanosterol 14α‑demethylase. Terbinafine often requires a shorter treatment duration for dermatophyte infections and may be preferred when rapid fungal clearance is desired.
What are the storage and handling requirements for Lamisil Once?+
Lamisil Once should be stored at room temperature, below 25 °C, in its original tube or container. Keep the product tightly closed, protect it from moisture and direct sunlight, and keep it out of reach of children.
How is Lamisil Once applied?+
Apply a thin layer of the cream to clean, dry skin on the affected area once daily. Gently rub it in until it disappears, and wash your hands after application unless the hands are being treated. Avoid covering the area with airtight dressings unless directed by a clinician.
What are the most serious risks associated with Lamisil Once?+
While rare, serious adverse reactions can include severe allergic responses such as rash, swelling, hives, or Stevens‑Johnson syndrome. Systemic toxicity, including liver enzyme elevations, has been reported in exceptional cases, especially when absorption is increased by occlusive dressings.
Who should not use Lamisil Once?+
Individuals with a known hypersensitivity to terbinafine, other allylamine antifungals, or any component of the cream should avoid its use. It should also not be applied to broken, inflamed or infected skin without medical advice, and caution is advised in patients with pre‑existing liver disease.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Terbinafine
Route
Cutaneous Use
Manufacturer
Karo Pharma Ab
Origin
EU

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