GNH USA

Europe — EMA

Lamisil Dermgel

GNH USA supplies Lamisil Dermgel (Terbinafine), an allylamine antifungal for athlete's foot, jock itch and ringworm. Request a quote for global supply.

Terbinafine

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What is Terbinafine?

Terbinafine, the active ingredient in Lamisil Dermgel, is an allylamine antifungal presented as a topical Dermgel for cutaneous use. It works by inhibiting fungal cell membrane synthesis and is indicated for the treatment of superficial dermatophyte infections such as athlete's foot, jock itch and ringworm in both adults and children.

GNH USA supplies Lamisil Dermgel as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide through regulated distribution channels, ensuring product integrity and compliance with local regulations.

What is Terbinafine used for?

Lamisil Dermgel (terbinafine) is used to treat dermatophyte infections of the skin. - Tinea pedis: resolves itching and scaling caused by athlete's foot. - Tinea cruris: reduces redness and inflammation associated with jock itch. - Tinea corporis: clears ring-shaped lesions of ringworm.

What are the side effects of Terbinafine?

Terbinafine topical therapy may be associated with local and systemic adverse reactions. Common Side Effects: - Application site irritation: redness, burning or itching at the site of gel application. - Pruritus: mild itching unrelated to infection. - Dry skin: localized dryness or peeling. - Erythema: mild redness of the treated area. Serious or Rare Side Effects: - Contact dermatitis: severe allergic skin reaction with swelling and vesicles. - Hepatotoxicity: rare liver enzyme elevation requiring monitoring. - Stevens‑Johnson syndrome: extremely rare severe mucocutaneous reaction. - Systemic hypersensitivity: anaphylaxis or severe rash.

What precautions apply to Terbinafine?

When using Lamisil Dermgel, several precautions should be observed to ensure safety and effectiveness. - Avoid use on broken skin: do not apply gel to open wounds or erosions. - Limit exposure to eyes: keep product away from ocular surfaces. - Monitor for allergic reaction: discontinue if severe rash or swelling occurs. - Use as directed: apply only the prescribed amount and frequency. - Pregnancy and lactation: consult a healthcare professional before use, as safety data are limited. - Store at room temperature: keep below 25 °C in the original packaging, protect from moisture and direct sunlight.

What does Terbinafine interact with?

Terbinafine may interact with other medicines; awareness of potential interactions helps avoid reduced efficacy or increased toxicity. Major Interactions (Avoid): - CYP2D6 inhibitors: co‑administration with strong CYP2D6 inhibitors can increase terbinafine levels. - Antifungal agents: concurrent use with other systemic antifungals may enhance toxicity. Moderate Interactions (Monitor Closely): - Warfarin: terbinafine may potentiate anticoagulant effect, requiring INR monitoring. - Oral contraceptives: possible reduction in efficacy, advise alternative contraception. - Antidepressants metabolized by CYP2C9: monitor for altered plasma concentrations.

Frequently asked questions

What conditions is Lamisil Dermgel used to treat?+
Lamisil Dermgel contains terbinafine and is indicated for the topical treatment of superficial dermatophyte infections such as tinea pedis (athlete's foot), tinea cruris (jock itch) and tinea corporis (ringworm). It works by eliminating the fungi that cause these skin conditions.
How does terbinafine work to fight fungal infections?+
Terbinafine belongs to the allylamine class and inhibits the fungal enzyme squalene epoxidase. This blocks the conversion of squalene to ergosterol, leading to toxic squalene buildup and loss of ergosterol, an essential component of the fungal cell membrane, resulting in fungal cell death.
What is the usual dose of Lamisil Dermgel?+
The appropriate amount and frequency of Lamisil Dermgel are determined by the prescribing healthcare professional based on the type and severity of the infection, patient age and other clinical factors. Patients should follow the specific instructions provided on the prescription label.
Is Lamisil Dermgel safe to use during pregnancy or breastfeeding?+
Safety data for topical terbinafine in pregnancy and lactation are limited. Women who are pregnant, planning pregnancy or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Lamisil Dermgel.
How do I order Lamisil Dermgel from GNH USA?+
To place an enquiry, visit the product page on gnh-usa.com, enter the required quantity and submit the request. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Lamisil Dermgel compare with other antifungal treatments?+
Compared with azole creams, terbinafine has a different mechanism—squalene epoxidase inhibition—and often requires a shorter treatment duration for dermatophyte infections. It is generally well‑tolerated, but choice of therapy should be guided by infection type, resistance patterns and clinician preference.
What are the recommended storage conditions for Lamisil Dermgel?+
Lamisil Dermgel should be stored at room temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture and direct sunlight, and keep it out of reach of children.
How is Lamisil Dermgel applied?+
The gel is applied thinly to the affected skin area, usually once or twice daily as directed by a healthcare professional. The skin should be clean and dry before application, and hands should be washed after use to avoid inadvertent contact with eyes or mucous membranes.
What are the most serious risks associated with Lamisil Dermgel?+
Although rare, serious adverse reactions can include severe allergic skin reactions such as contact dermatitis, systemic hypersensitivity including anaphylaxis, and, in exceptional cases, liver toxicity. Patients should discontinue use and seek medical attention if they experience swelling, blistering, jaundice or other severe symptoms.
Who should not use Lamisil Dermgel?+
Individuals with known hypersensitivity to terbinafine, other allylamine antifungals or any component of the gel should avoid its use. It is also contraindicated on extensive broken skin or mucous membranes, and caution is advised for pregnant or breastfeeding women until safety is confirmed by a clinician.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Terbinafine
Route
Cutaneous Use
Manufacturer
Karo Healthcare Ab
Origin
EU

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