GNH USA

Europe — EMA

Lamisil At

GNH USA supplies Lamisil At (Terbinafine), an allylamine antifungal for athlete’s foot, jock itch and ringworm. Request a quote for worldwide supply today.

Terbinafine

Request sourcing

1
Pack/s

What is Terbinafine?

Terbinafine, the active ingredient in Lamisil At, is an allylamine presented as a topical formulation for cutaneous use. It treats common fungal skin infections such as athlete’s foot, jock itch and ringworm in both adults and children, and is indicated for superficial dermatophyte infections of the skin and nails.

GNH USA supplies Lamisil At as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, adhering to EU quality standards and providing reliable logistics for global distribution through a robust supply chain.

What is Terbinafine used for?

Terbinafine is an allylamine antifungal that targets dermatophyte infections of the skin.

Athlete’s foot (tinea pedis): reduces fungal growth and alleviates itching and scaling. Jock itch (tinea cruris): eliminates the causative fungus and improves skin comfort. Ringworm (tinea corporis): clears the infection and promotes healing of lesions.

What are the side effects of Terbinafine?

Topical terbinafine may cause local and systemic adverse reactions, most of which are mild and reversible.

Common Side Effects: - Skin irritation: mild burning or stinging at the application site. - Itching: localized pruritus. - Redness: erythema around the treated area. - Dryness: peeling or flaking of the skin.

Serious or Rare Side Effects: - Allergic reaction: swelling, hives, or difficulty breathing. - Severe skin reaction: Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Liver toxicity: abnormal liver function tests observed rarely with extensive use.

What precautions apply to Terbinafine?

Before using Lamisil At, consider the following precautions to ensure safe and effective treatment.

- Pregnancy: consult a healthcare professional before application. - Breastfeeding: discuss potential risks with a physician. - Age: follow pediatric dosing recommendations if used in children. - Allergy: avoid if known hypersensitivity to terbinafine or other allylamines. - Application: apply to clean, dry skin and avoid contact with eyes. - Store at ambient temperature: keep in original packaging, protect from moisture and heat.

What does Terbinafine interact with?

Terbinafine can interact with other medicines; awareness of these interactions helps prevent adverse effects.

Major Interactions (Avoid): - Oral terbinafine: concurrent use may increase systemic exposure and toxicity. - Strong CYP2D6 inhibitors (e.g., fluoxetine, paroxetine): may raise terbinafine levels. - Warfarin: increased anticoagulant effect reported.

Moderate Interactions (Monitor Closely): - Oral contraceptives: efficacy may be reduced. - Antifungal agents (e.g., azoles): combined use can enhance irritation. - Alcohol: excessive intake may increase liver strain.

Frequently asked questions

What is Lamisil At used for?+
Lamisil At is a topical formulation containing terbinafine, an allylamine antifungal. It is indicated for the treatment of superficial fungal skin infections such as athlete’s foot (tinea pedis), jock itch (tinea cruris) and ringworm (tinea corporis). The medication works by eliminating the causative dermatophyte fungi and relieving associated symptoms.
How does terbinafine work?+
Terbinafine acts by inhibiting the fungal enzyme squalene epoxidase, which is essential for ergosterol synthesis in the cell membrane. Blocking this step leads to toxic accumulation of squalene and depletion of ergosterol, compromising membrane integrity and causing fungal cell death while sparing human cells that use a different cholesterol pathway.
What determines the dose of Lamisil At?+
The amount of Lamisil At to apply is determined by the prescribing healthcare professional based on the infection’s location, severity, patient age and skin condition. Patients should follow the specific instructions provided by their clinician and the product label, as dosing is not standardized across all cases.
Is Lamisil At safe during pregnancy or breastfeeding?+
Safety data for topical terbinafine in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Lamisil At. The prescriber will decide whether the treatment is appropriate.
How do I order Lamisil At from GNH USA?+
To order Lamisil At, submit an enquiry on the product page at gnh-usa.com indicating the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide. After the request, the sales team will verify trade or institutional credentials and respond with pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.
How does Lamisil At compare with other antifungal treatments?+
Lamisil At (terbinafine) belongs to the allylamine class, which differs from azole antifungals such as clotrimazole or miconazole. Allylamines target squalene epoxidase, offering a rapid fungicidal effect and often requiring shorter treatment durations. In contrast, azoles inhibit lanosterol 14‑α‑demethylase and may be more suitable for certain yeast infections. Choice of therapy depends on the pathogen, infection site and clinician preference.
How should Lamisil At be stored and handled?+
Lamisil At should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture, direct sunlight and excessive heat. Do not freeze the product. Handling should be performed with clean hands, and any unused portion should be discarded after the expiration date.
How is Lamisil At applied?+
Before application, wash and thoroughly dry the affected skin area. Apply a thin layer of Lamisil At to the lesion and the surrounding skin, usually once or twice daily as directed by the prescriber. Gently rub the cream or gel into the skin until it disappears, and wash hands after use to avoid accidental contact with eyes or mucous membranes.
What are the most serious risks associated with Lamisil At?+
While most reactions are mild, serious risks include severe allergic responses such as swelling, hives, or difficulty breathing, and rare but life‑threatening skin conditions like Stevens‑Johnson syndrome or toxic epidermal necrolysis. In very uncommon cases, systemic absorption may lead to liver enzyme abnormalities. Users should seek immediate medical attention if they experience any signs of a severe reaction.
Who should not use Lamisil At?+
Lamisil At should be avoided by individuals with known hypersensitivity to terbinafine, other allylamines, or any component of the formulation. It is also contraindicated in patients who have experienced severe cutaneous adverse reactions to topical antifungals. Children under the age specified on the product label should not use the medication unless directed by a qualified healthcare professional.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Terbinafine
Route
Cutaneous Use
Manufacturer
Karo Healthcare Ab
Origin
EU

Related products