GNH USA

Europe — EMA

Lamisil At

GNH USA supplies Lamisil At (Terbinafine), an allylamine antifungal for tinea corporis, tinea pedis, tinea cruris, and other dermatophyte infections.

Terbinafine Hydrochloride

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What is Terbinafine Hydrochloride?

Terbinafine, the active ingredient in Lamisil At, is an allylamine antifungal presented as a topical formulation for skin use. It treats dermatophyte infections of the skin and nails, such as athlete’s foot, ringworm, and jock itch, in adult and pediatric patients.

GNH USA supplies Lamisil At as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The product conforms to EU market standards and is manufactured under GMP conditions.

What is Terbinafine Hydrochloride used for?

Lamisil At is an allylamine antifungal used to treat infections caused by dermatophyte fungi.

- Tinea corporis: clears the skin rash and eliminates the causative fungus. - Tinea pedis: reduces itching and resolves athlete’s foot lesions. - Tinea cruris: alleviates inflammation in the groin area and eradicates fungal growth. - Tinea barbae: treats fungal infection of the beard region, restoring normal skin. - Dermatophytosis: provides broad‑spectrum control of skin‑surface fungal infections.

What are the side effects of Terbinafine Hydrochloride?

Common Side Effects: - Itching at the application site: mild to moderate discomfort. - Burning sensation: transient warmth during use. - Redness: localized erythema. - Scaling or flaking: dry skin patches. - Irritation: occasional stinging. - Dryness: reduced skin moisture.

Serious or Rare Side Effects: - Allergic reaction: swelling, hives, or difficulty breathing. - Severe skin rash: widespread redness or blistering. - Stevens‑Johnson syndrome: rare but life‑threatening mucocutaneous reaction. - Contact dermatitis: persistent inflammation at the site. - Urticaria: sudden hives. - Facial swelling: indicates systemic hypersensitivity.

What precautions apply to Terbinafine Hydrochloride?

Before using Lamisil At, consider the following precautions. - Pregnancy: consult a healthcare professional before application. - Breastfeeding: discuss potential risks with a physician. - Age restrictions: not recommended for children under 2 years unless directed by a clinician. - Pre‑existing skin conditions: avoid use on eczematous or inflamed skin. - Occlusion: do not cover the treated area with airtight dressings. - Store at room temperature: keep in the original container, protect from moisture and light.

What does Terbinafine Hydrochloride interact with?

Terbinafine topical may interact with other skin‑applied agents.

Major Interactions (Avoid): - Systemic terbinafine: concurrent use can increase systemic exposure. - Other topical antifungals: may cause additive irritation.

Moderate Interactions (Monitor Closely): - Topical corticosteroids: may reduce antifungal efficacy. - Alcohol‑based cleansers: can increase skin dryness. - Phototoxic agents: monitor for increased skin sensitivity to light.

Frequently asked questions

What conditions is Lamisil At used to treat?+
Lamisil At is a topical antifungal indicated for the treatment of dermatophyte infections such as tinea corporis (ringworm), tinea pedis (athlete’s foot), tinea cruris (jock itch), tinea barbae, and other forms of dermatophytosis affecting the skin.
How does terbinafine work to eliminate fungal infections?+
Terbinafine blocks the fungal enzyme squalene epoxidase, preventing the synthesis of ergosterol, an essential component of fungal cell membranes. This disruption leads to accumulation of toxic squalene and ultimately causes fungal cell death while sparing human cells.
What is the usual dose of Lamisil At?+
The specific dose and frequency of Lamisil At are determined by the prescribing healthcare professional based on the infection type, severity, patient age, and other clinical factors. Patients should follow the prescriber’s instructions exactly.
Is Lamisil At safe to use during pregnancy or while breastfeeding?+
Safety data for topical terbinafine during pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Lamisil At.
How do I order Lamisil At from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.
How does Lamisil At compare with other antifungal treatments?+
Compared with azole antifungals, terbinafine has a different mechanism—squalene epoxidase inhibition—offering rapid fungicidal activity. It is often preferred for dermatophyte infections due to its high efficacy and lower rates of resistance, though choice of therapy should be individualized by the clinician.
What are the recommended storage conditions for Lamisil At?+
Lamisil At should be stored at room temperature, below 25 °C, in its original packaging. Keep the product away from excess moisture, direct sunlight, and heat sources to maintain stability and potency.
How should Lamisil At be applied?+
Apply a thin layer of the cream to the affected skin area once or twice daily, as directed by the prescriber. Gently rub it in until fully absorbed, and wash hands before and after application to avoid accidental contact with eyes or mucous membranes.
What are the most serious risks associated with Lamisil At?+
Although rare, serious adverse reactions can include severe allergic responses such as swelling, hives, difficulty breathing, or a widespread skin rash like Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they experience any of these symptoms.
Who should not use Lamisil At?+
Lamisil At should be avoided in individuals with known hypersensitivity to terbinafine or any component of the formulation. It is also not recommended for children under two years of age unless specifically prescribed, and patients with extensive skin damage or severe eczema should consult a clinician before use.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Terbinafine Hydrochloride
Route
Cutaneous Use
Manufacturer
Karo Healthcare Ab
Origin
EU

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