GNH USA

Europe — EMA

Lakcid Entero

GNH USA supplies Lakcid Entero (Saccharomyces boulardii), a probiotic for antibiotic-associated diarrhea, Clostridioides difficile adjunct therapy, acute

Saccharomyces Boulardii

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What is Saccharomyces Boulardii?

Saccharomyces boulardii, the active ingredient in Lakcid Entero, is a probiotic presented as an oral preparation for oral use. It is used to help manage diarrhea associated with antibiotics, infections, and travel, and to support gut health in adults and children.

GNH USA supplies Lakcid Entero as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Saccharomyces Boulardii used for?

Lakcid Entero is a probiotic that acts on the gastrointestinal tract to restore microbial balance and reduce diarrheal symptoms. - Antibiotic‑associated diarrhea: helps re‑establish normal gut flora and shortens the duration of loose stools. - Clostridioides difficile infection (adjunct therapy): supports conventional treatment by limiting pathogen overgrowth. - Acute infectious diarrhea: reduces stool frequency and improves stool consistency during bacterial or viral gastroenteritis. - Travelers’ diarrhea: aids in maintaining intestinal homeostasis when exposure to unfamiliar pathogens occurs.

What are the side effects of Saccharomyces Boulardii?

Lakcid Entero is generally well tolerated, but some users may experience mild reactions.

Common Side Effects: - Abdominal bloating: mild, transient increase in gas. - Flatulence: excess intestinal gas. - Nausea: occasional feeling of queasiness. - Mild constipation: occasional reduced bowel movements.

Serious or Rare Side Effects: - Fungemia: rare bloodstream infection, primarily in severely immunocompromised patients. - Allergic reaction: rash, itching, or swelling that may require medical attention.

What precautions apply to Saccharomyces Boulardii?

Before using Lakcid Entero, consider the following precautions. - Immunocompromised patients: assess risk of opportunistic infection before administration. - Central venous catheters: avoid use if catheter is present due to potential translocation risk. - Pediatric use: follow prescriber guidance for children, especially infants. - Concomitant antifungal therapy: monitor for reduced probiotic efficacy. - Store below 25°C: keep in the original pack, protect from moisture and direct sunlight.

What does Saccharomyces Boulardii interact with?

Lakcid Entero may interact with certain medications, requiring attention to avoid reduced effectiveness or safety concerns.

Major Interactions (Avoid): - Systemic antifungal agents (e.g., fluconazole): may inhibit probiotic yeast viability. - Broad‑spectrum antibiotics taken concurrently: can diminish probiotic colonisation.

Moderate Interactions (Monitor Closely): - Immunosuppressants (e.g., corticosteroids, biologics): increase risk of systemic infection, monitor patient closely. - Antidiarrheal agents (e.g., loperamide): may alter gut motility, affecting probiotic distribution.

Frequently asked questions

What is Lakcid Entero used for?+
Lakcid Entero is an oral probiotic containing Saccharomyces boulardii. It is indicated for managing antibiotic‑associated diarrhea, serving as an adjunct in Clostridioides difficile infection, treating acute infectious diarrhea, and helping prevent or reduce symptoms of travelers’ diarrhea by supporting a balanced gut microbiome.
How does Saccharomyces boulardii work?+
The yeast strain Saccharomyces boulardii acts by colonising the intestinal lumen, competing with harmful bacteria for nutrients and adhesion sites, secreting enzymes that neutralise bacterial toxins, and modulating immune responses. It also strengthens tight‑junction proteins, improving the intestinal barrier and reducing fluid loss during diarrheal episodes.
What is the usual dose of Lakcid Entero?+
The dosage of Lakcid Entero is determined by the prescribing healthcare professional based on the patient’s age, condition, and clinical response. Typical regimens vary, and the prescriber will provide specific instructions on the number of capsules or sachets to be taken and the duration of therapy.
Is Lakcid Entero safe during pregnancy or breastfeeding?+
Safety data for Saccharomyces boulardii during pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before starting Lakcid Entero.
How do I order Lakcid Entero from GNH USA?+
To order Lakcid Entero, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the team will provide pricing, availability, shipping details (including any cold‑chain requirements), and assist with import documentation.
How does Lakcid Entero compare with other antidiarrheal probiotics?+
Lakcid Entero contains the yeast Saccharomyces boulardii, which differs from bacterial probiotics such as Lactobacillus or Bifidobacterium strains. Yeast‑based probiotics are resistant to antibiotics, making them useful during antibiotic therapy, and have demonstrated efficacy in preventing C. difficile recurrence. Bacterial probiotics may offer benefits in other contexts, but Saccharomyces boulardii’s unique mechanisms provide distinct clinical advantages for the indicated conditions.
How should Lakcid Entero be stored and handled?+
Store Lakcid Entero at temperatures below 25 °C, in a dry place away from direct sunlight. Keep the product in its original packaging to protect it from moisture. Do not refrigerate unless the label specifically advises otherwise, and avoid exposing the capsules or sachets to excessive heat or humidity.
How is Lakcid Entero administered?+
Lakcid Entero is taken orally. The capsules or sachets should be swallowed with a glass of water and can be taken with or without food, unless the prescribing clinician advises otherwise. Follow the prescriber’s instructions regarding timing relative to meals or other medications.
What are the most serious risks to watch for when using Lakcid Entero?+
While generally safe, the most serious risks include rare cases of systemic fungal infection (fungemia) and severe allergic reactions such as rash, swelling, or difficulty breathing. These events are uncommon and typically occur in patients with profound immunosuppression or central venous catheters. Prompt medical attention is required if any signs of infection or hypersensitivity appear.
Who should not use Lakcid Entero?+
Lakcid Entero should be avoided in individuals with known hypersensitivity to Saccharomyces boulardii or any excipients in the formulation. It is also contraindicated in patients with severe immunosuppression, those with indwelling central venous catheters, or anyone at high risk for invasive fungal infections unless specifically directed by a healthcare professional.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Saccharomyces Boulardii
Route
Oral Use
Manufacturer
Zaklady Farmaceutyczne Polpharma S.A.
Origin
EU

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