GNH USA

Europe — EMA

Lakafin

GNH USA supplies Lakafin (Tioconazole), a imidazole antifungal for athlete’s foot, jock itch and skin candidiasis. Request a quote for global supply.

Tioconazole

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What is Tioconazole?

Tioconazole, the active ingredient in Lakafin, is an imidazole antifungal presented as a topical cream for skin use. It treats superficial fungal infections of the feet, groin and other cutaneous sites in adults and children. By inhibiting fungal cell‑membrane synthesis, Tioconazole eradicates dermatophytes and Candida species, relieving itching, scaling and redness. The formulation allows easy local application with minimal systemic absorption.

GNH USA supplies Lakafin as a licensed, GDP‑compliant supplier serving pharmacies and clinics worldwide, ensuring reliable international delivery to healthcare providers.

What is Tioconazole used for?

Tioconazole is an imidazole antifungal that acts on dermatophyte and yeast infections of the skin.

- Tinea pedis: reduces fungal growth and alleviates itching, scaling and redness on the feet. - Tinea cruris: clears infection and relieves irritation in the groin area. - Cutaneous candidiasis: eliminates Candida overgrowth on skin, improving lesions and discomfort.

What are the side effects of Tioconazole?

Topical application of Tioconazole may cause local skin reactions.

Common Side Effects: - Burning sensation: mild transient feeling at the application site. - Itching: occasional pruritus where the cream is used. - Redness: localized erythema. - Stinging: brief sharp discomfort. - Dryness: skin may feel less moist. - Irritation: mild irritation of the treated area.

Serious or Rare Side Effects: - Allergic reaction: hives, swelling, or rash indicating hypersensitivity. - Contact dermatitis: severe inflammation of the skin. - Angioedema: rapid swelling of deeper skin layers. - Anaphylaxis: rare systemic allergic response requiring emergency care. - Severe skin blistering: extensive bullae formation. - Persistent swelling: prolonged edema at the site.

What precautions apply to Tioconazole?

Before using Lakafin, consider the following safety measures.

- Avoid use on broken skin: do not apply to open wounds or irritated areas. - Allergy check: discontinue if you have known hypersensitivity to azole antifungals. - Eye protection: keep the product away from eyes and mucous membranes. - Hand hygiene: wash hands thoroughly after application to prevent accidental spread. - Limit duration: use only for the prescribed period and avoid prolonged continuous use. - Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

What does Tioconazole interact with?

Tioconazole may interact with other substances applied to the skin or taken systemically.

Major Interactions (Avoid): - Concurrent use with other topical antifungals: may increase irritation risk. - Combination with systemic azole antifungals: can raise systemic absorption and toxicity.

Moderate Interactions (Monitor Closely): - Use with topical corticosteroids: may alter effectiveness or increase skin thinning. - Application over occlusive dressings: can enhance drug penetration and cause irritation. - Co‑application with alcohol‑based products: may affect drug stability. - Use with other irritant cosmetics: monitor for increased skin reactions.

Frequently asked questions

What is Lakafin used for?+
Lakafin contains the antifungal agent Tioconazole and is indicated for the topical treatment of superficial fungal infections such as athlete’s foot (tinea pedis), jock itch (tinea cruris) and cutaneous candidiasis. It helps to clear the infection, reduce associated itching, scaling and redness, and promote healing of the affected skin.
How does Tioconazole work?+
Tioconazole works by inhibiting the fungal enzyme lanosterol 14α‑demethylase, which is essential for the synthesis of ergosterol, a key component of fungal cell membranes. Disruption of ergosterol production compromises membrane integrity, leading to leakage of cellular contents and inhibition of fungal growth at the site of application.
What is the usual dose of Lakafin?+
The specific dosing regimen for Lakafin is determined by the prescribing healthcare professional based on the type and severity of the infection. Typically, a thin layer of the cream is applied to the affected area once or twice daily for the duration recommended by the prescriber. Patients should follow the instructions provided on the label or by their clinician.
Is Lakafin safe during pregnancy or breastfeeding?+
Safety data for Tioconazole use during pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss the potential risks and benefits with their healthcare provider before using Lakafin. The prescriber can decide whether an alternative therapy is more appropriate.
How do I order Lakafin from GNH USA?+
To order Lakafin, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the sales team provides pricing, availability, shipping details (including any cold‑chain requirements) and assists with import documentation.
How does Lakafin compare with other antifungal treatments?+
Lakafin’s active ingredient, Tioconazole, belongs to the imidazole class and offers a broad spectrum against dermatophytes and Candida species. Compared with allylamine agents such as terbinafine, imidazoles may have a slightly slower onset but are effective for both dermatophyte and yeast infections. The topical route limits systemic exposure, making it a convenient option for localized skin infections.
How should Lakafin be stored and handled?+
Lakafin should be stored at room temperature, preferably below 25 °C, in its original container. Keep the product away from direct sunlight, moisture and heat sources. Ensure the cap is tightly closed after each use to maintain product stability. Do not freeze the cream, and keep it out of reach of children.
How is Lakafin applied?+
Before applying Lakafin, wash and gently dry the affected area. Apply a thin layer of the cream to the lesion and the surrounding skin, gently massaging it in until fully absorbed. Wash your hands after application unless the hands are the treatment site. Use the product for the duration prescribed, even if symptoms improve earlier.
What are the most serious risks associated with Lakafin?+
Serious adverse reactions, although rare, include severe allergic responses such as hives, swelling, contact dermatitis, angioedema and anaphylaxis. If any signs of a systemic allergic reaction occur—such as difficulty breathing, facial swelling or widespread rash—stop using the product immediately and seek emergency medical attention.
Who should not use Lakafin?+
Lakafin should not be used by individuals with a known hypersensitivity to Tioconazole or any other imidazole antifungal. It is also contraindicated on broken, severely inflamed or infected skin where the barrier is compromised. Patients with a history of severe allergic reactions to topical medications should consult a healthcare professional before using Lakafin.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Tioconazole
Route
Cutaneous Use
Manufacturer
Verisfield S.M.S.A
Origin
EU

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