GNH USA

Europe — EMA

Lagroben

GNH USA supplies Lagroben (carmellose sodium), a ophthalmic lubricant for dry eye syndrome and ocular surface protection. Request a quote for supply.

Carmellose Sodium

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1
Pack/s

What is Carmellose Sodium?

Carmellose Sodium, the active ingredient in Lagroben, is a ophthalmic lubricant presented as an ophthalmic solution for topical ocular use. It treats dry eye syndrome and ocular surface irritation in adults. GNH USA supplies Lagroben as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Carmellose Sodium used for?

Lagroben (carmellose sodium) is used to manage dry eye and related ocular surface conditions.

- Dry eye syndrome: provides lubrication and stabilises the tear film to relieve discomfort. - Ocular surface irritation: reduces friction and protects the cornea from environmental stress. - Lubrication during ocular surgery: maintains moisture and protects ocular tissues intraoperatively.

What are the side effects of Carmellose Sodium?

Lagroben is generally well tolerated, but ocular preparations can cause local reactions.

Common Side Effects: - Transient burning or stinging sensation after instillation. - Temporary blurred vision. - Mild ocular redness. - Foreign‑body feeling in the eye. - Mild allergic conjunctivitis. - Slight eyelid swelling.

Serious or Rare Side Effects: - Severe allergic reaction, including anaphylaxis. - Corneal ulcer or epithelial defect. - Persistent eye pain. - Sudden loss of vision. - Severe intra‑ocular inflammation. - Secondary eye infection.

What precautions apply to Carmellose Sodium?

Before using Lagroben, consider the following safety measures.

- Allergy assessment: verify no known hypersensitivity to carmellose sodium or related compounds. - Contact lens wearers: remove lenses before instillation and wait before reinserting. - Concurrent eye medications: administer Lagroben at least 5 minutes apart to avoid dilution. - Pregnancy and lactation: use only if clearly needed, as safety data are limited. - Active eye infection: evaluate before use, as the product may mask symptoms. - Store at room temperature: keep in the original container, protect from light and moisture.

What does Carmellose Sodium interact with?

Lagroben may interact with other ophthalmic agents; monitor patients accordingly.

Major Interactions (Avoid): - Concurrent use with ophthalmic anesthetics: may increase corneal toxicity. - Use with preservative‑containing drops: risk of additive irritation. - Systemic antihistamines: may reduce tear production, diminishing therapeutic effect.

Moderate Interactions (Monitor Closely): - Contact lens solutions: may affect the viscosity of the drop. - Topical steroids: monitor for delayed corneal healing. - Anti‑glaucoma eye drops: observe intra‑ocular pressure for any unexpected changes.

Frequently asked questions

What is Lagroben used for?+
Lagroben is an ophthalmic lubricant containing carmellose sodium. It is indicated for the relief of dry eye syndrome, reduction of ocular surface irritation, and to provide moisture protection during ocular surgical procedures.
How does carmellose sodium work?+
Carmellose sodium is a cellulose derivative that increases the viscosity of the tear film. By thickening the tear layer, it prolongs tear residence time on the eye, improves lubrication, and creates a protective barrier that shields the cornea and conjunctiva from friction and environmental stress.
What is the usual dose of Lagroben?+
The dosing regimen for Lagroben is determined by the prescribing clinician based on the patient’s condition. Typically, one to two drops are instilled in the affected eye(s) as needed, but the exact frequency and duration should follow the healthcare professional’s instructions.
Is Lagroben safe in pregnancy or breastfeeding?+
Safety data for carmellose sodium in pregnancy and lactation are limited. It should be used only if clearly needed and after a risk‑benefit assessment by the prescriber. Women who are pregnant or breastfeeding should discuss potential risks with their healthcare provider.
How do I order Lagroben from GNH USA?+
To order Lagroben, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.
How does Lagroben compare with other eye lubricants?+
Lagroben’s active ingredient, carmellose sodium, provides high viscosity and long‑lasting lubrication, similar to hyaluronic acid‑based drops. Compared with simple saline solutions, Lagroben offers better tear‑film stability and longer symptom relief, making it a preferred option for moderate to severe dry eye and intra‑operative lubrication.
What are the storage and handling requirements for Lagroben?+
Lagroben should be stored at room temperature, below 25 °C, in its original container. Protect the bottle from direct sunlight, moisture and extreme temperatures. Keep the cap tightly closed when not in use to maintain sterility.
How is Lagroben administered?+
Lagroben is applied topically to the eye. The patient should wash their hands, tilt the head back, pull down the lower eyelid, and place one drop into the conjunctival sac. The eye can be closed gently for a few seconds to aid distribution.
What are the most serious risks associated with Lagroben?+
Although rare, serious adverse events include severe allergic reactions such as anaphylaxis, corneal ulceration, persistent eye pain, sudden loss of vision, and intra‑ocular inflammation. Any of these symptoms require immediate medical attention.
Who should not use Lagroben?+
Lagroben should be avoided in individuals with a known hypersensitivity to carmellose sodium or any excipients in the formulation. It is also contraindicated in eyes with active infection or severe inflammation until the underlying condition is treated.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Carmellose Sodium
Route
Ocular Use , Subconjunctival Use
Manufacturer
Teva Pharma S.L.U.,
Origin
EU

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