Europe — EMA
Ladinin
GNH USA supplies Ladinin (Ciprofloxacin Hydrochloride), a fluoroquinolone antibiotic for urinary, respiratory, skin and gastrointestinal infections.
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What is Ciprofloxacin Hydrochloride Monohydrate?
Ciprofloxacin Hydrochloride, the active ingredient in Ladinin, is a fluoroquinolone antibiotic presented as an oral formulation for systemic use. It treats a range of bacterial infections in adults, including urinary, respiratory, skin and soft‑tissue, and gastrointestinal infections. It is indicated for use in both community and hospital settings, offering a broad spectrum of activity against Gram‑negative and selected Gram‑positive pathogens.
GNH USA supplies Ladinin as a licensed, GDP‑compliant international pharmaceutical product to hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for each batch.
What is Ciprofloxacin Hydrochloride Monohydrate used for?
Ladinin (ciprofloxacin hydrochloride) is a fluoroquinolone antibiotic used to treat bacterial infections in various organ systems.
- Urinary tract infection: eradicates susceptible uropathogens, relieving symptoms and preventing complications. - Respiratory tract infection: eliminates common respiratory bacteria, aiding recovery from bronchitis and pneumonia. - Skin and soft tissue infection: clears susceptible skin pathogens, supporting wound healing. - Gastrointestinal infection: targets enteric bacteria, helping resolve dysentery and travel‑related diarrhoea.
What are the side effects of Ciprofloxacin Hydrochloride Monohydrate?
Ciprofloxacin may cause a variety of adverse reactions, ranging from mild to severe.
Common Side Effects: - Nausea or vomiting: mild gastrointestinal upset. - Diarrhea: loose stools that may be self‑limiting. - Headache: transient cranial discomfort. - Dizziness or light‑headedness: occasional vertiginous sensations.
Serious or Rare Side Effects: - Tendon rupture or inflammation: sudden pain in tendons, especially the Achilles. - Central nervous system effects: seizures, confusion, or hallucinations. - Severe allergic reactions: rash, angioedema, or anaphylaxis.
What precautions apply to Ciprofloxacin Hydrochloride Monohydrate?
Before prescribing Ladinin, consider the following precautions to ensure safe use. - Renal function: assess kidney function and adjust dose if impairment is present. - Allergy history: avoid in patients with known hypersensitivity to fluoroquinolones or related compounds. - Tendon health: discontinue if tendon pain, swelling, or inflammation occurs. - Central nervous system: monitor patients with a history of seizures or psychiatric disorders. - Pregnancy and lactation: use only when the potential benefit justifies the potential risk to the fetus or infant. - Store at ambient temperature: keep below 25 °C in the original packaging, protected from moisture and light.
What does Ciprofloxacin Hydrochloride Monohydrate interact with?
Ciprofloxacin can interact with several medicines; awareness of key interactions helps prevent adverse outcomes.
Major Interactions (Avoid): - Antacids containing magnesium or aluminum: significantly reduce ciprofloxacin absorption; separate administration by at least 2 hours. - Warfarin: may enhance anticoagulant effect, increasing bleeding risk; monitor INR closely. - Theophylline: ciprofloxacin can increase serum theophylline levels, risking toxicity.
Moderate Interactions (Monitor Closely): - Non‑steroidal anti‑inflammatory drugs (NSAIDs): may increase risk of CNS stimulation and seizures. - Diabetic agents (e.g., insulin, sulfonylureas): ciprofloxacin may alter glucose control; monitor blood sugar. - Corticosteroids: concurrent use may raise the chance of tendon disorders.
Frequently asked questions
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Product details
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