Lactulose Hexal

Lactulose, the active ingredient in Lactulose Hexal, is a osmotic laxative presented as an oral formulation for oral use. It is used to treat constipation and to reduce ammonia absorption in patients with hepatic encephalopathy. GNH USA supplies Lactulose Hexal as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Lactulose acts on the gastrointestinal tract to relieve constipation and to manage hepatic encephalopathy. - Constipation: softens stool and promotes regular bowel movements. - Hepatic encephalopathy: lowers intestinal ammonia levels, helping improve neurological symptoms.

Lactulose may cause a range of adverse reactions.

Common Side Effects: - Flatulence: increased gas production in the colon. - Abdominal cramping: mild to moderate discomfort. - Diarrhea: loose stools, especially at higher doses. - Nausea: feeling of queasiness. - Bloating: sensation of fullness. - Thirst: increased desire for fluids.

Serious or Rare Side Effects: - Severe electrolyte imbalance: especially low potassium or sodium. - Dehydration: significant fluid loss leading to dizziness. - Allergic reaction: rash, urticaria, or swelling. - Severe abdominal pain: may indicate colonic complications. - Hypernatremia: elevated blood sodium in rare cases.

Before using Lactulose, consider the following precautions. - Renal impairment: adjust dose and monitor renal function. - Electrolyte monitoring: check serum electrolytes during prolonged therapy. - Intestinal obstruction: avoid use if there is a known blockage. - Diabetes mellitus: be aware of the sugar content in the solution. - Hepatic disease: monitor for worsening encephalopathy. - Store at ambient temperature: keep below 25°C, retain in original container, protect from moisture and direct sunlight.

Lactulose can interact with other medicines; awareness helps prevent complications.

Major Interactions (Avoid): - Loop diuretics: combined use may exacerbate electrolyte loss. - Other osmotic laxatives: concurrent use can increase risk of severe diarrhea and dehydration.

Moderate Interactions (Monitor Closely): - Antibiotics altering gut flora (e.g., rifaximin): may affect lactulose metabolism. - Oral hypoglycemic agents: monitor blood glucose due to sugar content. - Antacids containing magnesium: may increase gastrointestinal side effects.