Lactulose Farmoz

Lactulose, the active ingredient in Lactulose Farmoz, is an osmotic laxative presented as an oral solution for oral use. It is used to treat constipation and to reduce intestinal ammonia absorption in patients with hepatic encephalopathy. GNH USA supplies Lactulose Farmoz as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Lactulose is an osmotic laxative that acts on the gastrointestinal tract to relieve constipation and lower ammonia levels in liver‑related conditions. - Constipation: softens stool and promotes bowel movements. - Hepatic encephalopathy: lowers intestinal ammonia to improve neurological symptoms. - Hyperammonemia: helps reduce elevated blood ammonia concentrations.

Lactulose may cause a range of adverse reactions, most of which are related to its laxative action.

Common Side Effects: - Abdominal cramping: discomfort due to increased bowel activity. - Flatulence: excess gas production from bacterial fermentation. - Diarrhoea: loose stools from osmotic effect. - Nausea: mild stomach upset. - Bloating: sensation of fullness. - Thirst: increased fluid loss.

Serious or Rare Side Effects: - Electrolyte imbalance: especially low potassium levels. - Severe dehydration: from excessive fluid loss. - Allergic reaction: rash, itching, or swelling. - Hypotension: due to fluid shifts. - Worsening hepatic encephalopathy: rare paradoxical effect.

Before prescribing Lactulose, clinicians should consider several safety aspects. - Dose adjustment in renal impairment: monitor renal function and adjust as needed. - Monitor electrolytes: especially potassium and sodium during prolonged use. - Avoid in galactosemia: patients with this metabolic disorder should not receive lactulose. - Caution in diabetes: sugar content may affect glycaemic control. - Pregnancy and lactation: consult a physician before use. - Store at ambient temperature: keep in the original pack, protect from moisture.

Lactulose can interact with other medications, requiring attention to avoid reduced efficacy or increased risk.

Major Interactions (Avoid): - Concurrent use with other strong laxatives: may cause severe diarrhoea and electrolyte loss. - Combination with diuretics: increased risk of dehydration and electrolyte disturbances.

Moderate Interactions (Monitor Closely): - Antacids: may alter gut pH and affect lactulose metabolism. - Probiotics: could modify bacterial fermentation and efficacy. - Oral hypoglycaemic agents: monitor blood glucose due to lactulose's sugar content.