Lactulose Aurobindo

Lactulose, the active ingredient in Lactulose Aurobindo, is an osmotic laxative presented as an oral formulation for oral use. It treats constipation and hepatic encephalopathy in appropriate patients.

GNH USA supplies Lactulose Aurobindo as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Lactulose acts on the gastrointestinal tract to relieve bowel stasis and to lower ammonia absorption in liver disease. - Constipation: promotes regular bowel movements by drawing water into the intestinal lumen. - Hepatic encephalopathy: reduces blood ammonia levels, helping to improve mental status in patients with liver dysfunction.

Lactulose may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects: - Abdominal cramping: discomfort due to increased intestinal activity. - Flatulence: excess gas production from bacterial fermentation. - Diarrhea: loose stools from osmotic water influx. - Nausea: mild upset stomach. - Bloating: sensation of fullness.

Serious or Rare Side Effects: - Electrolyte imbalance: significant loss of potassium or sodium. - Severe dehydration: excessive fluid loss leading to hypotension. - Allergic reaction: rash, itching, or swelling requiring medical attention.

Before initiating Lactulose therapy, consider the following safety measures. - Renal function assessment: monitor kidney status in patients with impaired renal clearance. - Electrolyte monitoring: check serum potassium and sodium during prolonged use. - Caution in hepatic impairment: adjust dose if liver function is severely compromised. - Avoid in intestinal obstruction: risk of worsening blockage. - Diabetes monitoring: observe blood glucose as lactulose may affect glycemic control. - Store below 25°C: keep in the original pack, protect from moisture and heat.

Lactulose can interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid): - Magnesium‑containing antacids: may increase osmotic load and cause severe diarrhea. - Other laxatives: combined use can lead to excessive fluid loss. - Antibiotics that disrupt gut flora: may reduce lactulose metabolism and effectiveness.

Moderate Interactions (Monitor Closely): - Oral hypoglycemics: possible alteration of glucose levels. - Diuretics: increased risk of electrolyte disturbances. - Probiotics: may modify bacterial fermentation of lactulose. - Sodium‑containing medications: monitor overall sodium balance.