GNH USA

Europe — EMA

Lacosamida Tarbis

GNH USA supplies Lacosamida Tarbis (Lacosamide), a anticonvulsant for partial‑onset seizures and adjunctive epilepsy therapy.

Lacosamide

Request sourcing

1
Pack/s

What is Lacosamide?

Lacosamide, the active ingredient in Lacosamida Tarbis, is an anticonvulsant presented as an intravenous solution for intravenous use. It is indicated for the treatment of partial‑onset seizures and is employed as adjunctive therapy in patients with epilepsy. The formulation meets EU regulatory standards and is produced under stringent quality‑control procedures.

GNH USA supplies Lacosamida Tarbis as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable sourcing for healthcare providers across multiple markets. The company adheres to Good Distribution Practices and ensures product integrity during transport.

What is Lacosamide used for?

Lacosamide is used in the management of seizure disorders, particularly partial‑onset epilepsy.

Partial‑onset seizures: reduces seizure frequency as add‑on therapy. Adjunctive therapy for epilepsy: enhances overall seizure control when combined with other antiepileptic drugs. Focal epilepsy: contributes to comprehensive management of patients with focal seizure types.

What are the side effects of Lacosamide?

Lacosamide may cause several adverse reactions, ranging from mild to serious.

Common Side Effects: - Dizziness: mild vertigo or light‑headedness. - Nausea: upset stomach or feeling of queasiness. - Headache: mild to moderate pain. - Fatigue: feeling unusually tired.

Serious or Rare Side Effects: - Cardiac conduction abnormalities: PR‑interval prolongation or arrhythmias. - Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Suicidal thoughts: emergence of depressive symptoms or suicidal ideation.

What precautions apply to Lacosamide?

When prescribing Lacosamide, consider the following precautions.

Renal impairment: adjust dosing and monitor renal function. Cardiac disease: monitor ECG for PR‑interval changes. Pregnancy: use only if benefits outweigh potential risks. Concomitant CNS depressants: observe for enhanced sedation. Hepatic dysfunction: evaluate liver enzymes. Store at ambient temperature: keep in original container, protect from light and moisture.

What does Lacosamide interact with?

Lacosamide can interact with other medicines; awareness of interaction severity is essential.

Major Interactions (Avoid): - Class I antiarrhythmics (e.g., quinidine): may increase PR‑interval prolongation. - Carbamazepine: induces metabolism, reducing lacosamide levels. - Strong CYP3A4 inhibitors (e.g., ketoconazole): may raise lacosamide exposure.

Moderate Interactions (Monitor Closely): - Other antiepileptics (e.g., phenytoin, phenobarbital): may alter seizure control. - Opioids: additive central nervous system depression. - Alcohol: increased sedation and dizziness.

Frequently asked questions

What is Lacosamida Tarbis used for?+
Lacosamida Tarbis contains lacosamide, an anticonvulsant indicated for the treatment of partial‑onset seizures and as adjunctive therapy in patients with epilepsy. It is administered intravenously to help control seizure activity when added to existing antiepileptic regimens.
How does lacosamide work?+
Lacosamide enhances the slow inactivation of voltage‑gated sodium channels in neurons, stabilizing hyperexcitable membranes and reducing repetitive firing. This mechanism diminishes neuronal hyperexcitability that underlies seizure generation, providing antiepileptic effects without markedly affecting normal neuronal conduction.
What is the usual dose of Lacosamida Tarbis?+
The dosage of Lacosamida Tarbis is determined by the prescribing clinician based on the patient’s clinical condition, age, renal function, and concomitant therapies. The prescriber will select an appropriate intravenous dosing regimen and adjust it as needed.
Is Lacosamida Tarbis safe during pregnancy or breastfeeding?+
Safety of lacosamide in pregnancy and lactation has not been fully established. It should be used only if the potential benefit justifies the potential risk to the fetus. Breastfeeding mothers should discuss possible exposure with their healthcare provider.
How do I order Lacosamida Tarbis from GNH USA?+
To request Lacosamida Tarbis, submit an enquiry on the product page at gnh-usa.com with the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and import documentation.
How does Lacosamida Tarbis compare with other antiepileptic drugs?+
Lacosamide’s unique mechanism—enhancing slow sodium‑channel inactivation—differs from many traditional antiepileptics that target fast inactivation. This can provide additive seizure control when combined with other agents, and it may have a lower risk of certain drug‑drug interactions compared with enzyme‑inducing antiepileptics.
What are the storage and handling requirements for Lacosamida Tarbis?+
Lacosamida Tarbis should be stored at ambient temperature, preferably below 25 °C, in its original packaging. Protect the solution from light and moisture, and keep it out of reach of children. Do not freeze the product.
How is Lacosamida Tarbis administered?+
The product is supplied as an intravenous solution and is administered by slow infusion into a vein under medical supervision. The infusion rate and duration are set by the treating physician according to the patient’s clinical needs.
What are the most serious risks associated with Lacosamida Tarbis?+
Serious risks include cardiac conduction abnormalities such as PR‑interval prolongation, severe skin reactions like Stevens‑Johnson syndrome, and emergence of suicidal thoughts or depressive symptoms. Patients should be monitored for these events, especially during treatment initiation or dose changes.
Who should not use Lacosamida Tarbis?+
Patients with known hypersensitivity to lacosamide or any component of the formulation should avoid the product. Caution is also advised for individuals with significant cardiac conduction disorders, severe hepatic impairment, or uncontrolled renal disease, where alternative therapies may be preferred.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Lacosamide
Route
Intravenous Use
Manufacturer
Tarbis Farma, S.L.
Origin
EU

Related products