Europe — EMA
Lacerol Hta Retard
GNH USA supplies Lacerol Hta Retard (Diltiazem Hydrochloride), a calcium channel blocker for hypertension and angina. Request a quote for global supply.
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What is Diltiazem Hydrochloride?
Diltiazem Hydrochloride, the active ingredient in Lacerol Hta Retard, is a calcium channel blocker presented as a modified‑release oral tablet for oral use. It treats hypertension and angina in adult patients. GNH USA supplies Lacerol Hta Retard as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Diltiazem Hydrochloride used for?
Lacerol Hta Retard, a calcium channel blocker, is employed in several cardiovascular conditions. - Hypertension: lowers elevated blood pressure by relaxing vascular smooth muscle. - Chronic stable angina: reduces frequency of chest pain episodes by improving myocardial oxygen supply. - Angina pectoris: alleviates acute chest discomfort through coronary vasodilation. - Certain cardiac arrhythmias: helps control heart rate by decreasing atrioventricular nodal conduction.
What are the side effects of Diltiazem Hydrochloride?
Common Side Effects: - Headache: mild to moderate pain often occurring early in therapy. - Flushing: transient warmth and redness of the skin. - Peripheral edema: swelling of the lower extremities due to fluid retention. - Dizziness: sensation of light‑headedness, especially when standing. - Nausea: mild gastrointestinal upset. - Constipation: reduced bowel motility.
Serious or Rare Side Effects: - Severe hypotension: markedly low blood pressure requiring medical attention. - Bradycardia: abnormally slow heart rate that may cause fatigue. - Heart block: impaired electrical conduction in the heart. - Hepatic dysfunction: abnormal liver enzyme elevations. - Severe allergic reaction: rash, swelling, or difficulty breathing. - Myocardial infarction: rare occurrence of heart attack.
What precautions apply to Diltiazem Hydrochloride?
Lacerol Hta Retard requires careful monitoring in several clinical situations. - Blood pressure monitoring: regularly assess to avoid excessive hypotension. - Heart rate assessment: watch for bradycardia, especially with concomitant beta‑blockers. - Hepatic impairment: use caution and consider dose adjustment in patients with liver disease. - Abrupt discontinuation: avoid sudden stop to prevent rebound hypertension. - Renal impairment: adjust dose in severe kidney dysfunction. - Store at room temperature: keep in the original pack, protect from moisture.
What does Diltiazem Hydrochloride interact with?
Diltiazem Hydrochloride can interact with various medicines, influencing its safety and efficacy. Major Interactions (Avoid): - Strong CYP3A4 inhibitors (e.g., ketoconazole): may increase diltiazem levels. - Beta‑blockers: combined use can cause marked bradycardia. - Digoxin: concurrent use may raise digoxin concentrations. Moderate Interactions (Monitor Closely): - CYP3A4 inducers (e.g., rifampin): may reduce diltiazem effectiveness. - NSAIDs: can diminish antihypertensive response. - Alcohol: may enhance dizziness and hypotension. - Diuretics: may potentiate blood‑pressure lowering effects.
Frequently asked questions
What conditions is Lacerol Hta Retard used for?+
How does diltiazem hydrochloride work in the body?+
What is the usual dose of Lacerol Hta Retard?+
Is Lacerol Hta Retard safe during pregnancy or breastfeeding?+
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How does Lacerol Hta Retard compare with other antihypertensive drugs?+
What are the storage and handling requirements for Lacerol Hta Retard?+
How is Lacerol Hta Retard administered?+
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Who should not use Lacerol Hta Retard?+
Product details
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