Labiriad

Aciclovir, the active ingredient in Labiriad, is an antiviral presented as a topical formulation for gingival use. It is employed to manage infections caused by the herpes simplex virus in the oral cavity and related tissues.

GNH USA supplies Labiriad as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Labiriad, an antiviral agent, is used to treat conditions caused by herpes simplex virus replication.

- Herpes labialis: reduces lesion duration and pain. - Herpes genitalis: alleviates symptoms and limits viral shedding. - Herpes simplex gingivostomatitis: controls oral lesions and promotes healing.

Adverse reactions may occur with topical gingival use of Labiriad.

Common Side Effects: - Local irritation: mild burning or stinging at the application site. - Redness: transient erythema of the gingiva. - Dryness: reduced salivary flow in the treated area. - Taste alteration: temporary metallic or bitter taste. - Mild swelling: localized edema.

Serious or Rare Side Effects: - Allergic reaction: rash, urticaria, or angioedema. - Severe mucosal ulceration: extensive tissue breakdown. - Systemic absorption effects: rare nephrotoxicity. - Stevens‑Johnson syndrome: severe skin and mucous membrane involvement. - Anaphylaxis: rapid onset of respiratory distress and hypotension.

When using Labiriad, consider the following safety measures.

- Assess allergy history: avoid if known hypersensitivity to aciclovir or related compounds. - Monitor renal function: caution in patients with impaired kidney function. - Use as directed: apply only to affected gingival areas. - Avoid concurrent ocular exposure: prevent contact with eyes. - Pregnancy and lactation: consult a healthcare professional before use. - Store at below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Labiriad may interact with other medicines; awareness of potential interactions is important.

Major Interactions (Avoid): - Probenecid: may increase systemic aciclovir levels. - Cimetidine: can reduce renal clearance of aciclovir.

Moderate Interactions (Monitor Closely): - NSAIDs: may increase risk of renal impairment. - Nephrotoxic agents (e.g., aminoglycosides): monitor kidney function. - Immunosuppressants: watch for altered viral activity. - Other antiviral agents: assess for additive toxicity.