Labentrol

Ciprofloxacin, the active ingredient in Labentrol, is a fluoroquinolone antibiotic presented as an oral tablet for oral use. It treats a broad range of bacterial infections in adult and pediatric patients when prescribed by a healthcare professional.

GNH USA supplies Labentrol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ciprofloxacin is a fluoroquinolone antibiotic that targets bacterial DNA replication, making it effective for several infection types. - Urinary tract infection: eradicates susceptible Gram‑negative bacteria causing uncomplicated cystitis. - Respiratory tract infection: treats acute exacerbations of chronic bronchitis and community‑acquired pneumonia. - Skin and soft‑tissue infection: combats susceptible Staphylococcus and Streptococcus species. - Gastrointestinal infection: effective against travel‑related diarrheal disease caused by susceptible organisms. - Bone and joint infection: used for osteomyelitis caused by susceptible bacteria.

Common side effects are generally mild and transient.

Common Side Effects: - Nausea: mild to moderate stomach upset. - Diarrhea: loose stools, occasionally watery. - Headache: transient cranial discomfort. - Dizziness: occasional light‑headedness. - Rash: mild skin erythema. - Photosensitivity: increased sunburn risk.

Serious or Rare Side Effects: - Tendon rupture: especially Achilles tendon, may occur without warning. - Peripheral neuropathy: numbness or tingling in extremities. - Clostridioides difficile infection: severe colitis. - Severe allergic reactions: anaphylaxis, angioedema. - QT interval prolongation: cardiac rhythm disturbances. - Hepatic toxicity: elevated liver enzymes or hepatitis.

Ciprofloxacin requires careful use in certain populations and conditions. - Renal impairment: dose adjustment may be needed. - History of tendon disorders: avoid use due to risk of tendon rupture. - Concomitant corticosteroid therapy: increased risk of tendon injury. - Cardiac conditions: monitor for QT prolongation. - Pregnancy and breastfeeding: safety not established; use only if clearly needed. - Store at ambient temperature below 25°C: keep in original packaging, protect from moisture and direct sunlight.

Ciprofloxacin can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid): - Antacids containing aluminum or magnesium: reduce ciprofloxacin absorption. - Iron supplements: significantly decrease drug bioavailability. - Warfarin: may increase anticoagulant effect and bleeding risk. - Cyclosporine: increased cyclosporine levels leading to toxicity. - Theophylline: elevated plasma concentrations causing toxicity.

Moderate Interactions (Monitor Closely): - NSAIDs: heightened risk of central nervous system stimulation. - Corticosteroids: additive risk of tendon rupture. - Diabetic agents: potential for hypoglycemia. - Oral hypoglycemics: may require dose adjustment. - Certain antiarrhythmics: monitor QT interval.