Labella

Levonorgestrel, the active ingredient in Labella, is a progestin presented as an oral tablet for oral use. It is employed to prevent pregnancy, including emergency contraception after unprotected intercourse. GNH USA supplies Labella as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Levonorgestrel acts on the hormonal pathways that regulate ovulation and implantation, making it suitable for contraception. - Emergency contraception: prevents pregnancy when taken shortly after unprotected sex. - Hormonal contraception: used as a regular method to inhibit ovulation and alter the endometrial lining. - Ovulation inhibition: suppresses the release of an egg when administered before the luteinizing hormone surge.

Levonorgestrel may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects: - Nausea: mild to moderate stomach upset. - Headache: occasional tension‑type headaches. - Breast tenderness: temporary discomfort in breast tissue. - Menstrual changes: spotting or altered cycle timing. - Dizziness: brief episodes of light‑headedness.

Serious or Rare Side Effects: - Thromboembolic events: rare blood clot formation. - Severe allergic reaction: hives, swelling, or anaphylaxis. - Liver dysfunction: abnormal liver enzyme levels. - Pregnancy complications: if taken during an unrecognized early pregnancy. - Persistent abdominal pain: may indicate underlying pathology.

Levonorgestrel should be used with awareness of specific safety considerations. - Contraindication: known hypersensitivity to levonorgestrel or any tablet excipients. - Pregnancy: not indicated for ongoing pregnancy; seek medical advice if pregnancy is suspected. - Hepatic impairment: use with caution in patients with liver disease. - Thromboembolic history: avoid in individuals with a history of clotting disorders. - Drug interactions: review concomitant medications (see interactions section). - Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Levonorgestrel can interact with several medicines, affecting its efficacy or safety.

Major Interactions (Avoid): - Rifampin: induces metabolism, reducing contraceptive effectiveness. - Anticonvulsants (e.g., carbamazepine, phenytoin): increase clearance, compromising efficacy. - St. John’s wort: herbal inducer that may lower drug levels. - HIV protease inhibitors (e.g., ritonavir): may alter hormonal activity. - Certain antibiotics (e.g., griseofulvin): can reduce contraceptive reliability.

Moderate Interactions (Monitor Closely): - Antifungals (ketoconazole, itraconazole): may increase hormone levels, requiring monitoring. - Antibiotics (tetracycline, metronidazole): potential modest reduction in effectiveness. - Hormonal therapies (combined oral contraceptives): may require dosage adjustments.