GNH USA

Europe — EMA

L-Thyroxin 150 1 A Pharma

GNH USA supplies L-Thyroxin 150 1 A Pharma (Levothyroxine), a thyroid hormone for hypothyroidism, thyroid hormone replacement after thyroidectomy

Levothyroxine Sodium

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What is Levothyroxine Sodium?

Levothyroxine, the active ingredient in L-Thyroxin 150 1 A Pharma, is a thyroid hormone presented as a 150 µg tablet for oral use. It treats hypothyroidism and is used in patients requiring thyroid hormone replacement after thyroidectomy or with goiter.

GNH USA supplies L-Thyroxin 150 1 A Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Levothyroxine Sodium used for?

Levothyroxine sodium acts on the thyroid hormone pathway to restore normal metabolic function in deficient patients.

Hypothyroidism: normalizes circulating thyroid hormone, alleviating fatigue, weight gain, cold intolerance, and other metabolic symptoms. Thyroid hormone replacement after thyroidectomy: supplies exogenous T4 to maintain metabolic rate and prevent hypothyroid complications post‑surgery. Goiter: reduces thyroid‑stimulating hormone drive, helping to stabilize or shrink an enlarged thyroid gland.

What are the side effects of Levothyroxine Sodium?

Levothyroxine may cause a range of adverse reactions, most of which are dose‑related.

Common Side Effects: - Headache: mild to moderate intensity. - Nausea: occasional gastrointestinal upset. - Insomnia: difficulty initiating sleep. - Palpitations: sensation of rapid or irregular heartbeat.

Serious or Rare Side Effects: - Cardiac arrhythmia: potentially life‑threatening rhythm disturbances. - Angina pectoris: chest pain due to myocardial ischemia. - Bone loss (osteoporosis): increased fracture risk with long‑term overtreatment.

What precautions apply to Levothyroxine Sodium?

When prescribing levothyroxine, clinicians should consider several safety measures. - Dose adjustment in elderly: start low and titrate slowly. - Monitor thyroid function tests: regularly assess TSH and free T4 levels. - Avoid abrupt discontinuation: taper if therapy must be stopped. - Caution in cardiovascular disease: assess cardiac status before initiating. - Store at ambient temperature: keep in the original pack, protect from moisture and light.

What does Levothyroxine Sodium interact with?

Levothyroxine absorption and metabolism can be affected by several concomitant drugs.

Major Interactions (Avoid): - Calcium or iron supplements: significantly reduce levothyroxine absorption. - Antacids containing aluminum or magnesium: interfere with gastrointestinal uptake.

Moderate Interactions (Monitor Closely): - Warfarin: levothyroxine may increase INR, requiring closer monitoring. - Amiodarone: can alter thyroid hormone levels and affect dosing. - Beta‑blockers: may mask symptoms of excess thyroid hormone.

Frequently asked questions

What is L-Thyroxin 150 1 A Pharma used for?+
L‑Thyroxin 150 µg tablets contain levothyroxine sodium and are indicated for thyroid hormone replacement in patients with hypothyroidism, for post‑thyroidectomy hormone therapy, and for the management of goiter. The medication supplies synthetic T4 to restore normal metabolic activity in individuals with insufficient endogenous thyroid hormone.
How does levothyroxine work?+
Levothyroxine is a synthetic analogue of the natural thyroid hormone thyroxine (T4). After oral absorption it is converted to the active form triiodothyronine (T3) inside cells, where it binds nuclear thyroid hormone receptors and regulates gene transcription that controls basal metabolic rate, protein synthesis, and growth, thereby correcting hormonal deficiency.
What is the usual dose of L-Thyroxin?+
The appropriate dose of L‑Thyroxin is individualized by the prescribing clinician based on age, weight, severity of hypothyroidism, and serum thyroid‑stimulating hormone (TSH) levels. Dosage adjustments are made during follow‑up to achieve target TSH values, and patients should follow the prescriber’s instructions without self‑adjusting the dose.
Is levothyroxine safe during pregnancy or breastfeeding?+
Levothyroxine is generally considered safe in pregnancy and lactation because adequate thyroid hormone is essential for fetal development and maternal health. However, dosing may need adjustment due to increased hormone requirements. Women who are pregnant, planning pregnancy, or breastfeeding should discuss therapy with their healthcare provider to ensure optimal management.
How do I order L-Thyroxin from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity of L‑Thyroxin 150 µg tablets. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.
How does L-Thyroxin compare with other thyroid hormone preparations?+
L‑Thyroxin contains levothyroxine sodium, the standard synthetic T4 used for most thyroid replacement therapies. Compared with combination T4/T3 products, levothyroxine offers a stable, once‑daily dosing regimen and a well‑characterized safety profile. It is generally preferred for primary hypothyroidism, while combination preparations may be reserved for specific cases where T3 supplementation is required.
What are the storage and handling requirements for L-Thyroxin?+
L‑Thyroxin tablets should be stored at ambient temperature, below 25 °C, in their original blister or bottle to protect from moisture and light. Keep the medication out of reach of children and avoid storing in bathrooms or near heat sources. Do not use if the packaging is damaged or the tablets appear discolored.
How is L-Thyroxin administered?+
L‑Thyroxin is taken orally, usually on an empty stomach, at least 30 minutes before breakfast or any other medication. Swallow the tablet whole with a full glass of water; do not crush or chew it. Consistent timing each day helps maintain stable serum hormone levels, and patients should follow the dosing schedule prescribed by their clinician.
What are the most serious risks associated with levothyroxine therapy?+
Serious risks include cardiac arrhythmias, angina, and exacerbation of osteoporosis, particularly when the dose is excessive or in patients with pre‑existing heart disease or bone loss. Over‑replacement can also cause symptoms of hyperthyroidism such as tremor, heat intolerance, and weight loss. Regular monitoring of thyroid function tests and clinical assessment helps mitigate these risks.
Who should not use L-Thyroxin?+
Levothyroxine is contraindicated in patients with untreated adrenal insufficiency, acute myocardial infarction, or uncorrected thyrotoxicosis. Individuals with known hypersensitivity to levothyroxine sodium or any excipients in the tablet should avoid its use. Clinicians should evaluate these conditions before initiating therapy and consider alternative management strategies when appropriate.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Levothyroxine Sodium
Route
Oral Use
Manufacturer
1 A Pharma Gmbh
Origin
EU

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