GNH USA

Europe — EMA

Ksilometazolinklorid/Ipratropijev Bromid Acino

GNH USA supplies Ksilometazolinklorid/Ipratropijev Acino (Xylometazoline/Ipratropium), a nasal decongestant for common cold, allergic rhinitis, and acute

Xylometazoline Hydrochloride, Ipratropium Bromide

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What is Xylometazoline Hydrochloride, Ipratropium Bromide?

Xylometazoline Hydrochloride and Ipratropium Bromide, the active ingredients in Ksilometazolinklorid/Ipratropijev Acino, are a combination nasal decongestant and anticholinergic presented as a nasal spray for nasal use. They treat nasal congestion associated with the common cold, allergic rhinitis and acute sinusitis in adults and children.

GNH USA supplies Ksilometazolinklorid/Ipratropijev Acino as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Xylometazoline Hydrochloride, Ipratropium Bromide used for?

Ksilometazolinklorid/Ipratropijev Acino acts on nasal mucosal vessels and glandular secretion to relieve congestion and discharge.

- Common cold nasal congestion: reduces swelling of nasal mucosa and improves airflow. - Allergic rhinitis: decreases nasal secretions and eases blockage. - Acute sinusitis: alleviates sinus pressure by opening nasal passages.

What are the side effects of Xylometazoline Hydrochloride, Ipratropium Bromide?

The following adverse reactions have been reported with the nasal spray.

Common Side Effects: - Nasal irritation or burning sensation. - Dryness of the nasal mucosa. - Sneezing or mild epistaxis. - Headache. - Altered taste or bitter taste. - Transient nasal itching.

Serious or Rare Side Effects: - Severe nasal bleeding. - Allergic reaction including rash, swelling, or anaphylaxis. - Paradoxical worsening of congestion (rebound congestion). - Cardiac arrhythmia (rare). - Acute glaucoma in susceptible individuals.

What precautions apply to Xylometazoline Hydrochloride, Ipratropium Bromide?

Before using Ksilometazolinklorid/Ipratropijev Acino, consider the following safety measures. - Pregnancy: consult a healthcare professional before use. - Breastfeeding: use with caution and under medical advice. - Children under 2 years: avoid use unless specifically prescribed. - Prolonged use (>7 days): discontinue to prevent rebound congestion. - Recent nasal surgery or trauma: postpone use until healed. - Store at room temperature: keep in the original container, protect from moisture and light.

What does Xylometazoline Hydrochloride, Ipratropium Bromide interact with?

Ksilometazolinklorid/Ipratropijev Acino may interact with other medicines as follows.

Major Interactions (Avoid): - Monoamine oxidase inhibitors (MAOIs): risk of hypertensive crisis. - Other nasal decongestants: additive vasoconstriction may increase cardiovascular strain. - Systemic sympathomimetics: potential for excessive blood pressure elevation.

Moderate Interactions (Monitor Closely):\n- Anticholinergic drugs: increased anticholinergic load may cause dry mouth or urinary retention. - Antihistamines: may enhance nasal dryness. - Inhaled beta‑agonists: monitor for tachycardia or palpitations.

Frequently asked questions

What is Ksilometazolinklorid/Ipratropijev Acino used for?+
Ksilometazolinklorid/Ipratropijev Acino is a nasal spray that combines Xylometazoline Hydrochloride and Ipratropium Bromide to relieve nasal congestion and reduce excess secretions caused by the common cold, allergic rhinitis, and acute sinusitis.
How does Xylometazoline Hydrochloride work?+
Xylometazoline Hydrochloride acts as an alpha‑adrenergic agonist, causing the blood vessels in the nasal lining to constrict. This vasoconstriction reduces swelling and opens the airway, providing rapid decongestion.
What is the usual dose of this product?+
The appropriate dose and frequency are determined by the prescribing healthcare professional based on the patient’s age, condition, and response. Patients should follow the prescriber’s instructions and the product label.
Is this medication safe during pregnancy or breastfeeding?+
Safety in pregnancy and lactation has not been fully established. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using the spray.
How do I order Ksilometazolinklorid/Ipratropijev Acino from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does this product compare with other nasal decongestants?+
Unlike single‑agent decongestants, this combination adds an anticholinergic (Ipratropium) to the vasoconstrictor (Xylometazoline), offering both reduced swelling and decreased watery discharge. This dual action can be more effective for patients with prominent rhinorrhea, but the safety profile and duration of use should be considered.
What are the storage and handling requirements?+
Store the nasal spray at room temperature, below 25 °C, in its original packaging. Keep it away from moisture, direct sunlight, and extreme temperatures to maintain product stability.
How is the spray administered?+
The spray is applied directly into each nostril, usually one or two sprays per nostril as directed by a healthcare professional. The patient should tilt the head slightly forward, close the opposite nostril, and gently inhale while actuating the pump.
What are the most serious risks to watch for?+
Serious adverse events, though rare, include severe nasal bleeding, allergic reactions such as rash or anaphylaxis, paradoxical worsening of congestion after prolonged use, and, in susceptible individuals, acute glaucoma. Any of these symptoms require immediate medical attention.
Who should not use this nasal spray?+
The spray should be avoided in individuals with known hypersensitivity to Xylometazoline, Ipratropium, or any excipients, in children under two years of age unless prescribed, and in patients with recent nasal surgery or severe nasal septum perforation without medical guidance.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Xylometazoline Hydrochloride, Ipratropium Bromide
Route
Nasal Use
Manufacturer
Acino France Sas
Origin
EU

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