Kruidvat

Paracetamol, the active ingredient in Kruidvat, is an analgesic presented as an oral tablet for oral use. It is classified as a pain reliever and antipyretic and is commonly employed to treat mild to moderate pain such as headache, muscular aches, and to lower elevated body temperature in both adults and children when taken as directed.

GNH USA supplies Kruidvat as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies, hospitals and clinics worldwide. The company adheres to stringent quality standards and regulatory requirements across EU markets.

Paracetamol acts centrally to alleviate pain and reduce fever.

- Headache: provides relief of tension‑type and mild migraine pain. - Fever: lowers elevated body temperature in febrile illnesses. - Muscular pain: eases soreness associated with minor strains or over‑exertion. - Toothache: reduces discomfort from dental pain. - Arthralgia: helps manage mild joint pain.

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Nausea: mild stomach upset after ingestion. - Abdominal discomfort: transient stomach pain. - Rash: mild skin irritation or itching. - Dizziness: occasional light‑headedness.

Serious or Rare Side Effects: - Severe skin reactions: such as Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Hepatotoxicity: liver injury, especially with overdose or chronic high dosing. - Blood disorders: rare cases of agranulocytosis or thrombocytopenia. - Anaphylaxis: rare allergic reaction requiring immediate medical attention.

Paracetamol should be used with attention to specific safety considerations.

- Dosage adjustment: reduce dose in patients with hepatic impairment. - Alcohol consumption: avoid excessive alcohol while using. - Allergy: discontinue if hypersensitivity reactions occur. - Pregnancy: use only if benefit outweighs risk (Category B). - Drug interactions: review concomitant medications for potential interactions. - Store at ambient temperature: keep below 25°C in the original pack, protect from moisture.

Paracetamol can interact with several medicines; monitoring is advised.

Major Interactions (Avoid): - Warfarin: may increase anticoagulant effect and bleeding risk. - Isoniazid: combined use raises risk of hepatotoxicity. - Carbamazepine: may reduce paracetamol efficacy. - Alcohol: potentiates liver toxicity.

Moderate Interactions (Monitor Closely): - Ciprofloxacin: may increase plasma concentration of paracetamol. - Phenobarbital: may increase metabolism, lowering effectiveness.