Kruidvat

Diclofenac potassium, the active ingredient in Kruidvat, is a nonsteroidal anti-inflammatory drug presented as an oral tablet for oral use. It treats mild to moderate pain, arthritis and other inflammatory musculoskeletal conditions in adults. GNH USA supplies Kruidvat as a licensed, GDP-compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Diclofenac potassium acts on inflammatory pathways to relieve pain and swelling in several common conditions.

- Mild to moderate pain: provides rapid analgesia for headaches, dental pain, and postoperative discomfort. - Osteoarthritis and rheumatoid arthritis: reduces joint inflammation and improves mobility. - Musculoskeletal injuries: alleviates pain and swelling associated with sprains, strains and soft‑tissue trauma.

Adverse reactions may occur with diclofenac potassium use.

Common Side Effects: - Nausea: mild to moderate upset stomach. - Dyspepsia: indigestion or heartburn. - Headache: transient cranial discomfort. - Dizziness: occasional light‑headedness. - Abdominal pain: cramping or discomfort. - Diarrhoea: loose stools.

Serious or Rare Side Effects: - Gastrointestinal ulcer or bleeding: potentially life‑threatening. - Hepatic injury: elevated liver enzymes or hepatitis. - Renal impairment: reduced kidney function or failure. - Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Anaphylaxis: acute allergic response. - Cardiovascular events: increased risk of heart attack or stroke.

Before using diclofenac potassium, consider the following safety measures.

- Assess gastrointestinal risk: avoid in patients with a history of ulcers or bleeding. - Monitor renal function: use caution in those with kidney disease or dehydration. - Use the lowest effective dose: limit duration to the shortest period needed. - Avoid in known hypersensitivity: discontinue if allergic reactions occur. - Caution with anticoagulants: increased bleeding risk when combined. - Store at room temperature: keep in the original pack, protect from moisture.

Diclofenac potassium can interact with several medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): heightened bleeding risk. - Other NSAIDs or aspirin: additive gastrointestinal toxicity. - Lithium: increased lithium serum levels. - Methotrexate: reduced clearance leading to toxicity.

Moderate Interactions (Monitor Closely):\n- ACE inhibitors or ARBs: possible reduction in renal function. - Diuretics: risk of electrolyte imbalance. - Corticosteroids: synergistic ulcerogenic effect. - Beta‑blockers: may blunt antihypertensive response. - Selective serotonin reuptake inhibitors: modest increase in bleeding tendency.