Kolekalciferol Evolan

Colecalciferol, the active ingredient in Kolekalciferol Evolan, is a Vitamin D presented as an oral supplement for oral use. It is used to treat vitamin D deficiency and related bone disorders in children and adults. By enhancing calcium and phosphate absorption, it supports normal bone mineralisation and helps prevent conditions such as osteomalacia and rickets.

GNH USA supplies Kolekalciferol Evolan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Kolekalciferol Evolan, a vitamin D supplement, is indicated for conditions related to impaired calcium metabolism.

- Vitamin D deficiency: restores adequate serum 25‑hydroxyvitamin D levels to support calcium balance. - Osteomalacia: promotes bone mineralisation and reduces bone pain in adults. - Rickets: aids proper bone growth and prevents skeletal deformities in children. - Prevention of bone loss: supports maintenance of bone health in at‑risk populations.

Oral colecalciferol may be associated with a range of adverse reactions, most of which are dose‑related.

Common Side Effects: - Nausea: mild gastrointestinal upset. - Constipation: reduced bowel movements. - Dry mouth: sensation of oral dryness. - Headache: mild to moderate head discomfort.

Serious or Rare Side Effects: - Hypercalcemia: elevated blood calcium causing weakness, confusion, or cardiac arrhythmia. - Kidney stones: calcium deposition in the renal tract. - Severe allergic reaction: rash, swelling, or anaphylaxis.

When using Kolekalciferol Evolan, several safety considerations should be observed.

- Baseline calcium assessment: check serum calcium before initiating therapy. - Renal function monitoring: evaluate kidney function periodically. - Avoid in hypercalcemia: discontinue if serum calcium is high. - Caution in granulomatous diseases: conditions such as sarcoidosis may increase vitamin D activation. - Pregnancy and lactation: safety not established; use only if clearly needed. - Store at below 25°C: keep in the original pack, protect from moisture.

Colecalciferol can affect or be affected by other medicines.

Major Interactions (Avoid): - Thiazide diuretics: may increase risk of hypercalcemia. - High-dose vitamin A: synergistic hypercalcemia risk. - Calcium supplements: excessive calcium load can cause hypercalcemia.

Moderate Interactions (Monitor Closely): - Anticonvulsants (e.g., phenytoin, phenobarbital): may reduce vitamin D effectiveness. - Glucocorticoids: can impair vitamin D metabolism. - Bariatric surgery or malabsorption syndromes: may decrease absorption of oral vitamin D.