Kohle-Tabletten

Activated charcoal, the active ingredient in Kohle-Tabletten, is an intestinal adsorbent presented as a tablet for oral use. It treats acute oral poisoning, drug overdose, and reduction of intestinal gas in adults and children as directed by a healthcare professional.

GNH USA supplies Kohle-Tabletten as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Activated charcoal is used as an intestinal adsorbent for gastrointestinal decontamination. - Acute oral poisoning: binds ingested toxins and limits systemic absorption. - Drug overdose: adsorbs excess medication in the gut to reduce toxicity. - Intestinal gas: reduces bloating by binding gas‑producing substances.

Activated charcoal may cause several adverse reactions, most of which are mild and transient.

Common Side Effects: - Constipation: reduced bowel movements may occur. - Black stools: discoloration due to charcoal passage. - Nausea or vomiting: gastrointestinal irritation. - Abdominal discomfort: mild cramping or bloating. - Flatulence: excess gas production. - Taste alteration: temporary metallic taste.

Serious or Rare Side Effects: - Aspiration: risk if vomited and inhaled, leading to respiratory complications. - Allergic reactions: rash, itching, or urticaria indicating hypersensitivity. - Severe constipation or bowel obstruction: may require medical intervention. - Electrolyte imbalance: rare but possible with prolonged use. - Gastrointestinal hemorrhage: uncommon but serious bleeding event.

When using Kohle-Tabletten, consider the following safety measures. - Dosage adjustment: modify dose in patients with reduced gastrointestinal motility. - Medical supervision: required for children, pregnant or breastfeeding women. - Avoid concurrent use: do not take with oral medications that require absorption unless spaced appropriately. - Hydration: maintain adequate fluid intake to prevent constipation. - Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Activated charcoal can affect the absorption of several concomitant agents.

Major Interactions (Avoid): - Antacids: may reduce charcoal's adsorption capacity. - Oral medications: charcoal can bind many drugs, decreasing their effectiveness. - Iron supplements: adsorption may impair iron absorption.

Moderate Interactions (Monitor Closely): - Warfarin: monitor INR as charcoal may affect anticoagulant levels. - Lithium: observe serum lithium concentrations. - Phenobarbital: may require dose adjustment due to reduced absorption.