Klotrimazol Pliva

Clotrimazole, the active ingredient in Klotrimazol Pliva, is an imidazole antifungal presented as a vaginal formulation for intravaginal use. It treats vaginal candidiasis and other yeast infections of the vagina in adult women.

GNH USA supplies Klotrimazol Pliva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent manufacturing standards and provides reliable logistics for consistent product availability across global markets.

Clotrimazole acts on fungal cell membranes to treat infections within the vaginal tract.

- Vaginal candidiasis: treatment of acute yeast infection of the vagina. - Recurrent vulvovaginal candidiasis: helps reduce the frequency of recurring episodes. - Yeast infection of the vagina: alleviates symptoms such as itching, burning and abnormal discharge.

Clotrimazole may cause local adverse reactions when applied intravaginally.

Common Side Effects: - Irritation or burning at the application site. - Itching or mild discomfort. - Vaginal discharge that may be watery or whitish. - Dryness of the vaginal mucosa. - Unpleasant odor.

Serious or Rare Side Effects: - Allergic reaction such as rash, hives, or swelling. - Severe skin reactions including Stevens‑Johnson syndrome. - Swelling of the face, lips or tongue. - Difficulty breathing or throat tightness. - Rare liver toxicity manifested by jaundice or abnormal liver tests.

Before using Klotrimazol Pliva, consider the following precautions.

- Assess for hypersensitivity: discontinue if signs of allergic reaction appear. - Avoid use if there is a known non‑Candida vaginal infection. - Do not apply during active menstrual bleeding if irritation is present. - Consult a healthcare professional before use during pregnancy or breastfeeding. - Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Clotrimazol may interact with other topical or systemic agents.

Major Interactions (Avoid): - Concurrent systemic azole antifungals may increase systemic exposure and toxicity. - Use with other irritating vaginal products may exacerbate local irritation.

Moderate Interactions (Monitor Closely): - Co‑administration with spermicides may reduce antifungal efficacy. - Use with hormonal contraceptives generally shows no significant interaction but monitoring is advised. - Simultaneous use of multiple vaginal medications may affect absorption and effectiveness.