Kloramfenikol Minims Bausch + Lomb Ireland Limited

Chloramphenicol, the active ingredient in Kloramfenikol Minims, is an amphenicol presented as an ophthalmic solution for ocular use. It treats bacterial conjunctivitis and other ocular surface infections in patients requiring topical antibiotic therapy.

GNH USA supplies Kloramfenikol Minims as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Chloramphenicol is an antibiotic used to treat bacterial infections of the eye.

- Bacterial conjunctivitis: reduces bacterial load, relieving redness, discharge and discomfort. - Ocular surface infection: eradicates susceptible organisms and supports healing of corneal lesions. - Post‑operative ocular prophylaxis: prevents bacterial contamination after eye surgery.

Adverse reactions may occur with topical chloramphenicol use.

Common Side Effects: - Stinging or burning sensation on instillation. - Temporary blurred vision. - Mild eye irritation or redness. - Localized allergic contact dermatitis.

Serious or Rare Side Effects: - Corneal ulceration. - Severe allergic reaction, including anaphylaxis. - Vision loss. - Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Toxic keratitis.

Use chloramphenicol eye drops only as directed and consider the following precautions.

- Hypersensitivity: avoid in patients with known allergy to chloramphenicol or other amphenicols. - Severe ocular surface damage: do not use on compromised corneas without specialist advice. - Duration of therapy: limit to the prescribed period to reduce resistance risk. - Monitor for allergic reactions: discontinue if severe irritation or systemic signs develop. - Store at room temperature: keep in the original container, protect from light and moisture.

Chloramphenicol eye drops can interact with systemic and topical agents.

Major Interactions (Avoid): - Systemic aminoglycosides: may increase ototoxicity risk. - Systemic anticoagulants: potential enhancement of anticoagulant effect. - Systemic carbamazepine: heightened risk of bone‑marrow suppression.

Moderate Interactions (Monitor Closely): - Topical non‑steroidal anti‑inflammatory drugs: may increase ocular irritation. - Other topical antibiotics: possible antagonistic effects. - Systemic CYP450 inhibitors: could raise chloramphenicol plasma levels.