Kloramfenikol Dak

Chloramphenicol, the active ingredient in Kloramfenikol Dak, is an amphenicol presented as an unknown strength/unknown form for ocular use. It treats bacterial conjunctivitis and other bacterial ocular infections in patients requiring topical antibiotic therapy.

GNH USA supplies Kloramfenikol Dak as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Kloramfenikol Dak is an ocular antibiotic indicated for bacterial infections of the eye surface.

- Bacterial conjunctivitis: reduces bacterial load and accelerates resolution of redness and discharge. - Bacterial keratitis: helps eradicate pathogenic bacteria and supports corneal healing. - Post‑operative ocular infection: prevents or treats bacterial contamination after eye surgery.

Adverse reactions may occur with topical ocular use of chloramphenicol.

Common Side Effects: - Eye irritation: mild burning or stinging on instillation. - Redness: transient conjunctival hyperemia. - Itching: localized pruritus. - Blurred vision: temporary visual disturbance. - Tearing: increased lacrimation. - Foreign body sensation: feeling of grit in the eye.

Serious or Rare Side Effects: - Allergic reaction: swelling, rash, or hives around the eye. - Stevens‑Johnson syndrome: severe mucocutaneous eruption. - Vision loss: sudden decrease in visual acuity. - Severe eye pain: indicative of deeper infection. - Systemic toxicity: rare bone‑marrow suppression if absorbed in large amounts. - Contact dermatitis: skin inflammation around the peri‑ocular area.

Use chloramphenicol eye drops with caution and follow medical guidance.

- Hypersensitivity: avoid if patient has known allergy to chloramphenicol or other amphenicols. - Corneal ulcer: do not use in active corneal ulcer without physician supervision. - Prolonged therapy: limit duration to prescribed period to reduce resistance risk. - Systemic absorption: monitor for signs of bone‑marrow suppression in extensive use. - Pregnancy and lactation: prescribe only if benefit outweighs potential risk. - Store at room temperature: keep in original container, protect from moisture and light.

Chloramphenicol may interact with other medicines; some require avoidance, others monitoring.

Major Interactions (Avoid): - Warfarin: may enhance anticoagulant effect, increasing bleeding risk. - Carbamazepine: can increase risk of bone‑marrow suppression. - Phenytoin: may potentiate hematologic toxicity.

Moderate Interactions (Monitor Closely): - Other topical antibiotics: assess for additive ocular irritation. - Non‑steroidal anti‑inflammatory eye drops: monitor for increased inflammation. - Oral contraceptives: possible reduction in efficacy, advise alternative contraception.