Klektica

Levofloxacin, the active ingredient in Klektica, is a fluoroquinolone antibiotic presented as an oral tablet for oral use. It treats a range of bacterial infections, including respiratory tract, urinary tract, skin and soft‑tissue, sinus and prostatitis, primarily in adult patients. It is indicated for adult patients with confirmed bacterial infections and is commonly prescribed when susceptibility testing supports its use.

GNH USA supplies Klektica as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, sourcing the product from EU‑regulated manufacturers and adhering to stringent quality and regulatory standards.

Levofloxacin is a broad‑spectrum fluoroquinolone that targets bacterial DNA replication, making it useful for several infection types.

- Respiratory tract infections: effective in treating community‑acquired pneumonia, acute bacterial sinusitis and bronchitis. - Urinary tract infections: clears uncomplicated and complicated UTIs caused by susceptible organisms. - Skin and soft‑tissue infections: resolves cellulitis, wound infections and abscesses. - Sinusitis: provides rapid bacterial eradication in acute sinus infections. - Prostatitis: treats bacterial prostatitis and reduces symptom recurrence.

Levofloxacin may cause a variety of adverse reactions, ranging from mild to severe.

Common Side Effects: - Nausea - Diarrhea - Headache - Dizziness

Serious or Rare Side Effects: - Tendon rupture or inflammation - QT interval prolongation leading to arrhythmia - Severe allergic reactions such as anaphylaxis

When prescribing Levofloxacin, clinicians should consider several safety precautions to minimize risk.

- Assess renal function: dose adjustment may be required in impaired clearance. - Avoid in patients with known tendon disorders: risk of tendonitis or rupture. - Monitor cardiac status: watch for QT prolongation, especially with other QT‑prolonging agents. - Use with caution in pregnancy or breastfeeding: safety category is unknown, weigh benefits versus risks. - Review concomitant medications: check for potential drug‑drug interactions that may increase toxicity. - Store at below 25°C: keep in the original pack, protect from moisture.

Levofloxacin can interact with other medicines, altering its efficacy or safety profile.

Major Interactions (Avoid): - Non‑steroidal anti‑inflammatory drugs (NSAIDs): increased risk of tendon rupture. - QT‑prolonging drugs (e.g., quinidine, moxifloxacin): additive effect on cardiac repolarisation. - Antacids or supplements containing aluminum, magnesium, calcium, or iron: markedly reduce levofloxacin absorption. - Warfarin: potentiates anticoagulant effect, increasing bleeding risk.

Moderate Interactions (Monitor Closely): - Corticosteroids: combined use may heighten tendon injury risk. - Diabetes medications (e.g., insulin, sulfonylureas): possible hyperglycaemia. - Theophylline: levofloxacin may raise plasma theophylline concentrations.