GNH USA

Europe — EMA

Klacid Paediatric Suspension

GNH USA supplies Klacid Paediatric Suspension (Clarithromycin), a macrolide antibiotic for bacterial infections in children.

Clarithromycin

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What is Clarithromycin?

Clarithromycin, the active ingredient in Klacid Paediatric Suspension, is a macrolide antibiotic presented as an oral suspension for pediatric use. It inhibits bacterial protein synthesis and is indicated for the treatment of a range of bacterial infections in children.

GNH USA supplies Klacid Paediatric Suspension as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU quality standards and provides reliable global distribution to meet clinical demand.

What is Clarithromycin used for?

Clarithromycin is a macrolide antibiotic used to treat bacterial infections in the pediatric population.

- Acute otitis media: reduces bacterial load and alleviates ear pain in children. - Community‑acquired pneumonia: clears the infection and improves respiratory function. - Streptococcal pharyngitis: eradicates streptococcal bacteria and relieves throat symptoms. - Sinusitis: treats bacterial sinus inflammation and restores normal sinus drainage. - Skin and soft‑tissue infections: eliminates causative bacteria and promotes healing of lesions.

What are the side effects of Clarithromycin?

Common Side Effects: - Diarrhea: loose stools may occur during treatment. - Nausea: feeling of sickness or upset stomach. - Taste alteration: a metallic or bitter taste is often reported. - Abdominal pain: discomfort or cramps in the stomach area. - Vomiting: expulsion of stomach contents.

Serious or Rare Side Effects: - Severe allergic reactions: rash, swelling, or anaphylaxis. - Hepatic dysfunction: elevated liver enzymes or jaundice. - QT interval prolongation: may lead to cardiac arrhythmias. - Clostridioides difficile infection: severe colitis after antibiotic use. - Anaphylaxis: life‑threatening hypersensitivity reaction.

What precautions apply to Clarithromycin?

Before prescribing Klacid Paediatric Suspension, consider the following precautions: - Dose adjustment in renal impairment: reduce dose as advised by the prescriber. - Monitor liver function: clarithromycin may elevate transaminases. - Avoid use in patients with known macrolide hypersensitivity: risk of allergic reaction. - Caution in patients taking drugs that prolong QT interval: may increase cardiac risk. - Use during pregnancy only if clearly needed: limited data on safety. - Store at ambient temperature: keep in original container, protect from moisture and light.

What does Clarithromycin interact with?

Clarithromycin interacts with several medicines; awareness helps prevent adverse events.

Major Interactions (Avoid): - Simvastatin and lovastatin: increased risk of myopathy. - Ergotamine derivatives: risk of severe vasospasm. - Pimozide: may cause serious cardiac arrhythmias.

Moderate Interactions (Monitor Closely): - Theophylline: clarithromycin can raise plasma concentrations. - Warfarin: may enhance anticoagulant effect and raise INR.

Frequently asked questions

What is Klacid Paediatric Suspension used for?+
Klacid Paediatric Suspension is a clarithromycin‑based oral suspension indicated for the treatment of a variety of bacterial infections in children, including ear infections, pneumonia, throat infections, sinusitis, and skin or soft‑tissue infections.
How does clarithromycin work?+
Clarithromycin binds to the 50S subunit of bacterial ribosomes, blocking the translocation step of protein synthesis. This stops the formation of essential proteins, inhibiting bacterial growth and allowing the immune system to clear the infection.
What is the usual dose of Klacid Paediatric Suspension?+
The dose of Klacid Paediatric Suspension is determined by the prescribing clinician based on the child’s age, weight, the type of infection, and renal or hepatic function. No fixed regimen is provided here.
Is Klacid Paediatric Suspension safe during pregnancy or breastfeeding?+
Safety data for clarithromycin in pregnancy and lactation are limited. It should be used only if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified health professional.
How do I order Klacid Paediatric Suspension from GNH USA?+
To order, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.
How does Klacid compare with the main alternative drug or class?+
The primary alternative to clarithromycin in children is azithromycin, another macrolide. Both share a similar mechanism, but azithromycin has a longer half‑life allowing once‑daily dosing, whereas clarithromycin often requires multiple daily doses. Resistance patterns and specific infection types may guide the choice.
How should Klacid Paediatric Suspension be stored and handled?+
Store the suspension at ambient temperature, below 25 °C, in the original container. Protect it from moisture, direct sunlight and extreme temperatures. Shake well before each use to ensure uniform drug distribution.
How is Klacid Paediatric Suspension administered?+
Klacid Paediatric Suspension is taken orally. Before each dose, shake the bottle thoroughly, then measure the prescribed amount with a calibrated oral syringe or dosing spoon. It can be given with or without food, unless the prescriber advises otherwise.
What are the most serious risks to watch for while using Klacid Paediatric Suspension?+
Serious risks include severe allergic reactions such as anaphylaxis, liver injury indicated by jaundice or elevated enzymes, cardiac arrhythmias due to QT prolongation, and Clostridioides difficile‑associated colitis. Any signs of these conditions require immediate medical attention.
Who should not use Klacid Paediatric Suspension?+
Children with a known hypersensitivity to clarithromycin, other macrolides, or any component of the formulation should not use this product. It is also contraindicated in patients with a history of significant QT prolongation or those taking drugs that strongly interact with clarithromycin without appropriate monitoring.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Clarithromycin
Route
Oral Use
Manufacturer
Viatris Healthcare Limited
Origin
EU

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