GNH USA

Europe — EMA

Kivizidiale

GNH USA supplies Kivizidiale (Timolol/Travoprost), a beta‑blocker/prostaglandin analog for open‑angle glaucoma and ocular hypertension. Request a quote today.

Timolol, Travoprost

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What is Timolol, Travoprost?

Timolol and Travoprost, the active ingredients in Kivizidiale, are a beta‑blocker and prostaglandin analog presented as eye drops for ocular use. They are employed to lower intra‑ocular pressure in patients with open‑angle glaucoma and ocular hypertension. GNH USA supplies Kivizidiale as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Timolol, Travoprost used for?

Kivizidiale combines timolol and travoprost to reduce intra‑ocular pressure in glaucoma‑related conditions.

Open‑angle glaucoma: lowers pressure to slow optic nerve damage. Ocular hypertension: reduces pressure to prevent progression to glaucoma. Post‑surgical ocular hypertension: assists in maintaining target pressure after eye surgery.

What are the side effects of Timolol, Travoprost?

Kivizidiale may cause ocular and systemic reactions.

Common Side Effects: - Eye irritation or burning sensation. - Blurred vision shortly after instillation. - Redness of the conjunctiva. - Dry eye or foreign‑body feeling. - Mild headache. - Transient eyelash changes.

Serious or Rare Side Effects: - Severe allergic reaction with swelling or rash. - Sudden loss of vision. - Marked eye pain or inflammation. - Paradoxical increase in intra‑ocular pressure. - Systemic bradycardia or hypotension. - Exacerbation of asthma or COPD.

What precautions apply to Timolol, Travoprost?

Before prescribing Kivizidiale, clinicians should consider several safety aspects. - Assess cardiovascular status: timolol may lower heart rate and blood pressure. - Screen for respiratory disease: avoid in patients with asthma or severe COPD. - Monitor intra‑ocular pressure regularly to ensure therapeutic response. - Advise patients not to wear contact lenses immediately after dosing. - Use only if benefits outweigh risks during pregnancy or lactation. - Store at room temperature: keep in the original container, protect from light and moisture.

What does Timolol, Travoprost interact with?

Kivizidiale can interact with other medications, requiring careful management.

Major Interactions (Avoid): - Non‑selective systemic beta‑blockers (e.g., propranolol): additive bradycardic effects. - Sympathomimetic ophthalmic agents (e.g., phenylephrine): may diminish pressure‑lowering efficacy.

Moderate Interactions (Monitor Closely):\n- Other ocular hypotensive agents (e.g., latanoprost): increased risk of ocular irritation. - Topical anesthetics: potential corneal toxicity. - Systemic antihypertensives: may enhance timolol‑induced blood pressure reduction.

Frequently asked questions

What is Kivizidiale used for?+
Kivizidiale is a prescription eye‑drop formulation that combines timolol and travoprost to lower intra‑ocular pressure. It is indicated for the management of open‑angle glaucoma and ocular hypertension, helping to prevent optic nerve damage and preserve visual function.
How does the combination of timolol and travoprost work?+
Timolol reduces the production of aqueous humor by blocking beta‑adrenergic receptors in the eye, while travoprost increases uveoscleral outflow by acting as a prostaglandin F2α analog. The dual mechanism provides a complementary pressure‑lowering effect.
What is the usual dose of Kivizidiale?+
The prescribed dose is determined by the treating eye‑care professional. Typically, one drop is instilled in the affected eye(s) once daily, but the exact regimen, including any adjustments, should follow the prescriber’s instructions.
Is Kivizidiale safe during pregnancy or breastfeeding?+
Safety data for timolol/travoprost in pregnancy and lactation are limited. The product should only be used when the potential benefit justifies any possible risk to the fetus or infant, and decisions should be made by a qualified healthcare provider.
How do I order Kivizidiale from GNH USA?+
Enquiries can be submitted on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Kivizidiale compare with other glaucoma eye‑drop therapies?+
Compared with monotherapy agents such as latanoprost or timolol alone, Kivizidiale offers a combined mechanism that often achieves greater intra‑ocular pressure reduction. This can simplify treatment regimens by reducing the need for multiple separate drops.
What are the storage and handling requirements for Kivizidiale?+
Store the eye‑drops at room temperature, preferably below 25 °C. Keep the bottle in its original packaging, protect it from direct light and moisture, and ensure the cap is tightly closed when not in use.
How is Kivizidiale administered?+
The patient should wash hands, tilt the head back, and gently pull down the lower eyelid to create a small pocket. One drop is placed into the conjunctival sac, avoiding contact between the tip and the eye or eyelashes. The eye should be closed gently for a few seconds to aid absorption.
What are the most serious risks associated with Kivizidiale?+
Serious adverse events include severe allergic reactions, sudden loss of vision, marked eye pain, paradoxical rise in intra‑ocular pressure, systemic bradycardia or hypotension, and worsening of asthma or COPD. Patients should seek immediate medical attention if any of these occur.
Who should not use Kivizidiale?+
Kivizidiale is contraindicated in patients with known hypersensitivity to timolol, travoprost, or any excipients, and in those with severe sinus bradycardia, advanced heart block, or uncontrolled asthma. Caution is also advised for individuals with severe chronic obstructive pulmonary disease.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Timolol, Travoprost
Route
Ocular Use
Manufacturer
Bausch + Lomb Ireland Limited
Origin
EU

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