GNH USA

Europe — EMA

Kivizidiale

GNH USA supplies Kivizidiale (Timolol/Travoprost), a beta blocker/prostaglandin analog combination for open-angle glaucoma and ocular hypertension.

Timolol, Travoprost

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What is Timolol, Travoprost?

Timolol, the active ingredient in Kivizidiale, is a beta blocker / prostaglandin analog combination presented as an ophthalmic solution (eye drops) for ocular (topical) use. It treats open-angle glaucoma and ocular hypertension in adults. GNH USA supplies Kivizidiale as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Timolol, Travoprost used for?

Kivizidiale is used to manage intraocular pressure in conditions affecting the eye's drainage pathways. - Open‑angle glaucoma: reduces intraocular pressure to slow optic nerve damage. - Ocular hypertension: lowers pressure to prevent progression to glaucoma. - Primary open‑angle glaucoma: maintains target pressure to preserve visual field.

What are the side effects of Timolol, Travoprost?

Kivizidiale may cause ocular and systemic reactions.

Common Side Effects: - Eye irritation or burning sensation. - Blurred vision shortly after instillation. - Conjunctival hyperemia (red eye). - Dry eye or foreign‑body feeling.

Serious or Rare Side Effects: - Allergic eye reaction with swelling or severe redness. - Sudden loss of vision or marked eye pain. - Increased intraocular pressure despite therapy. - Systemic beta‑blocker effects such as bradycardia or bronchospasm.

What precautions apply to Timolol, Travoprost?

Before prescribing Kivizidiale, clinicians should evaluate patient‑specific risk factors. - Cardiovascular assessment: monitor for bradycardia or hypotension. - Respiratory status: avoid in patients with asthma or severe COPD. - Ocular surface disease: use with caution in severe dry eye or corneal disorders. - Hypersensitivity: discontinue if allergic reaction occurs. - Concomitant ocular drugs: assess for additive pressure‑lowering effects. - Store at room temperature: keep bottle tightly closed, protect from light and moisture.

What does Timolol, Travoprost interact with?

Kivizidiale can interact with other medications that affect ocular or systemic beta‑adrenergic pathways.

Major Interactions (Avoid): - Systemic non‑selective beta‑blockers: may cause additive bradycardia or hypotension. - Concurrent prostaglandin analog eye drops: increase risk of ocular inflammation.

Moderate Interactions (Monitor Closely): - Topical NSAIDs: may exacerbate corneal irritation. - Systemic antihypertensives: monitor blood pressure for additive lowering. - Other intraocular pressure‑lowering agents: adjust dosing to avoid over‑reduction of pressure.

Frequently asked questions

What is Kivizidiale used for?+
Kivizidiale is an ophthalmic solution indicated for the reduction of intraocular pressure in patients with open‑angle glaucoma and ocular hypertension. By lowering pressure within the eye, it helps to prevent optic nerve damage and preserve visual function.
How does the combination of Timolol and Travoprost work?+
Timolol reduces the production of aqueous humor by blocking beta‑adrenergic receptors in the ciliary body, while Travoprost increases uveoscleral outflow by acting as a prostaglandin F2α analog. Together they address both the inflow and outflow pathways, providing a synergistic pressure‑lowering effect.
What is the usual dose of Kivizidiale?+
The dosing regimen for Kivizidiale is determined by the prescribing ophthalmologist based on the individual patient's intraocular pressure, response to therapy, and tolerance. Typically, one drop is instilled in the affected eye(s) once daily, but the exact schedule should follow the prescriber’s instructions.
Is Kivizidiale safe during pregnancy or breastfeeding?+
Safety data for Kivizidiale in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant. Healthcare providers should discuss individual risks and consider alternative treatments when appropriate.
How do I order Kivizidiale from GNH USA?+
To request Kivizidiale, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Kivizidiale compare with other glaucoma eye drops?+
Compared with single‑agent therapies, Kivizidiale combines a beta‑blocker and a prostaglandin analog, offering dual mechanisms that can achieve greater intraocular pressure reduction with a single daily dose. This may improve adherence versus using two separate drops, though individual response varies.
What are the storage and handling requirements for Kivizidiale?+
Kivizidiale should be stored at room temperature, below 25 °C, in its original container. Keep the bottle tightly closed, protect it from light and moisture, and discard any solution that appears discolored or contains particles.
How is Kivizidiale administered?+
The medication is applied as an eye drop. The patient should wash hands, tilt the head back, pull down the lower eyelid to form a pocket, and instill one drop into the conjunctival sac. Close the eye gently and avoid blinking excessively for a few seconds.
What are the most serious risks associated with Kivizidiale?+
Serious risks include severe allergic reactions in the eye, sudden loss of vision, marked increase in intraocular pressure despite treatment, and systemic beta‑blocker effects such as bradycardia, hypotension, or bronchospasm, especially in patients with pre‑existing cardiac or respiratory conditions.
Who should not use Kivizidiale?+
Kivizidiale is contraindicated in patients with known hypersensitivity to timolol, travoprost, or any excipients in the formulation. It should also be avoided in individuals with severe asthma, chronic obstructive pulmonary disease, or certain cardiac conduction disorders where systemic beta‑blockade could be harmful.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Timolol, Travoprost
Route
Ocular Use
Manufacturer
Bausch + Lomb Ireland Limited
Origin
EU

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