GNH USA

Europe — EMA

Kivizidiale

GNH USA supplies Kivizidiale (Timolol/Travoprost), a beta blocker/prostaglandin analog for open-angle glaucoma and ocular hypertension. Request a quote.

Timolol, Travoprost

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What is Timolol, Travoprost?

Timolol and Travoprost, the active ingredients in Kivizidiale, are a beta‑blocker and a prostaglandin analog presented as eye drops for ocular use. They are prescribed to lower intraocular pressure in patients with open‑angle glaucoma and ocular hypertension.\n\nGNH India supplies Kivizidiale as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Timolol, Travoprost used for?

Kivizidiale is used in the management of glaucoma and related ocular pressure disorders.\n\nOpen‑angle glaucoma: reduces intraocular pressure to prevent optic nerve damage.\nOcular hypertension: lowers eye pressure to reduce the risk of progression to glaucoma.\nSecondary glaucoma (adjunctive therapy): assists in controlling pressure when monotherapy is insufficient.

What are the side effects of Timolol, Travoprost?

Kivizidiale may cause ocular and systemic adverse reactions.\n\nCommon Side Effects:\n- Eye irritation or burning sensation\n- Blurred vision\n- Redness of the eye\n- Dry eye or foreign‑body sensation\n\nSerious or Rare Side Effects:\n- Severe allergic reaction (e.g., angio‑edema)\n- Exacerbation of asthma or chronic obstructive pulmonary disease\n- Cardiac arrhythmia or bradycardia\n- Sudden loss of vision\n- Deep ocular pain

What precautions apply to Timolol, Travoprost?

Before prescribing Kivizidiale, consider the following precautions.\n\nMonitor intraocular pressure: adjust therapy based on pressure readings.\nAssess respiratory status: avoid in patients with active asthma or severe COPD.\nEvaluate cardiac function: caution in bradycardia, heart block, or heart failure.\nAvoid concurrent ocular beta‑blocker use: risk of additive systemic effects.\nStore at room temperature: keep in the original container, protect from light and moisture.

What does Timolol, Travoprost interact with?

Kivizidiale can interact with other medications; awareness of interaction severity is important.\n\nMajor Interactions (Avoid):\n- Systemic non‑selective beta‑blockers (e.g., propranolol): may cause additive bradycardia or hypotension.\n- Other ocular beta‑blocker preparations: increase risk of systemic beta‑blockade.\n- Systemic carbonic anhydrase inhibitors: may enhance intraocular pressure‑lowering effect leading to over‑reduction.\n\nModerate Interactions (Monitor Closely):\n- Topical corticosteroids: may increase intraocular pressure when used together.\n- Anticholinergic eye drops: potential for reduced efficacy of timolol.

Frequently asked questions

What is Kivizidiale used for?+
Kivizidiale is a prescription eye‑drop formulation containing timolol and travoprost. It is used to lower intraocular pressure in patients with open‑angle glaucoma and ocular hypertension, helping to prevent optic nerve damage and preserve visual function.
How does timolol and travoprost work in Kivizidiale?+
Timolol reduces aqueous humor production by blocking β‑adrenergic receptors in the ciliary body, while travoprost increases uveoscleral outflow by activating prostaglandin F2α receptors. The dual mechanism results in a greater reduction of intraocular pressure than either agent alone.
What is the usual dose of Kivizidiale?+
The dosing regimen for Kivizidiale is determined by the prescribing clinician based on the patient’s condition, response, and tolerance. Typically, one drop is instilled in the affected eye(s) once daily, but the exact schedule should follow the prescriber’s instructions.
Is Kivizidiale safe during pregnancy or breastfeeding?+
Safety data for Kivizidiale in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision should be made by the treating physician after a thorough risk‑benefit assessment.
How do I order Kivizidiale from GNH USA?+
To order Kivizidiale, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Kivizidiale compare with other glaucoma eye drops?+
Kivizidiale combines a beta‑blocker (timolol) with a prostaglandin analog (travoprost), offering a synergistic pressure‑lowering effect. Compared with monotherapy agents, the combination can achieve greater intraocular pressure reduction, potentially reducing the need for multiple separate drops.
What are the storage and handling requirements for Kivizidiale?+
Kivizidiale should be stored at room temperature, below 25 °C, in its original container. Keep the bottle tightly closed, protect it from light and moisture, and discard any solution that appears discolored or contains particles.
How is Kivizidiale administered?+
Kivizidiale is administered as an ocular drop. The patient should wash their hands, tilt the head back, pull down the lower eyelid to create a pocket, and place one drop into the eye. Close the eye gently and avoid blinking excessively for a few seconds.
What are the most serious risks associated with Kivizidiale?+
Serious risks include severe allergic reactions, worsening of asthma or chronic obstructive pulmonary disease, significant bradycardia or cardiac arrhythmias, sudden loss of vision, and deep ocular pain. Patients should seek immediate medical attention if any of these symptoms occur.
Who should not use Kivizidiale?+
Kivizidiale is contraindicated in patients with known hypersensitivity to timolol, travoprost, or any excipients, as well as those with severe asthma, chronic obstructive pulmonary disease, sinus bradycardia, second‑ or third‑degree heart block, or uncontrolled heart failure.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Timolol, Travoprost
Route
Ocular Use
Manufacturer
Bausch + Lomb Ireland Limited
Origin
EU

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