GNH USA

Europe — EMA

Kivizidiale

GNH USA supplies Kivizidiale (Timolol / Travoprost), a beta blocker/prostaglandin combo for open-angle glaucoma and ocular hypertension. Request a quote.

Timolol, Travoprost

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What is Timolol, Travoprost?

Timolol and Travoprost, the active ingredients in Kivizidiale, are a beta blocker/prostaglandin analog combination presented as ocular drops for ophthalmic use. It treats primary open-angle glaucoma and ocular hypertension by lowering intra‑ocular pressure. GNH USA supplies Kivizidiale as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Timolol, Travoprost used for?

Kivizidiale is used in the management of glaucoma and related ocular pressure disorders. - Primary open-angle glaucoma: reduces intra‑ocular pressure to slow disease progression. - Ocular hypertension: lowers eye pressure to prevent development of glaucoma. - Post‑surgical pressure control: maintains target pressure after laser or surgical procedures.

What are the side effects of Timolol, Travoprost?

Common Side Effects: - Eye irritation or burning sensation: mild discomfort after instillation. - Blurred vision: transient visual disturbance. - Redness of the eye: conjunctival hyperemia. - Dry eye: reduced tear production. - Foreign body sensation: feeling of grit. - Ocular discomfort: mild itching or stinging.

Serious or Rare Side Effects: - Severe allergic reaction: swelling, rash, or difficulty breathing. - Eyelid swelling: significant edema around the lid. - Persistent eye pain: prolonged discomfort requiring medical review. - Vision loss: sudden decrease in visual acuity. - Systemic beta‑blocker effects: bradycardia, hypotension, or bronchospasm.

What precautions apply to Timolol, Travoprost?

Before using Kivizidiale, consider the following precautions. - Monitor intra‑ocular pressure: assess pressure after initiation and adjust therapy as needed. - Assess cardiovascular status: use cautiously in patients with bradycardia, heart block, or asthma. - Avoid concurrent beta‑blocker eye drops: duplication may increase systemic exposure. - Review systemic beta‑blocker therapy: inform ophthalmologist of any oral beta‑blocker use. - Pregnancy and lactation: use only if clearly needed after risk‑benefit evaluation. - Store at room temperature: keep in the original container, protect from light and moisture.

What does Timolol, Travoprost interact with?

Kivizidiale may interact with other medications. Major Interactions (Avoid): - Systemic beta‑blockers: additive cardiovascular depression may occur. - Other ocular beta‑blocker preparations: risk of excessive beta‑blockade. - Additional prostaglandin analogs: increased ocular irritation. Moderate Interactions (Monitor Closely): - Anticholinergic eye drops: may reduce efficacy of pressure lowering. - Topical corticosteroids: potential increase in intra‑ocular pressure. - Beta‑agonist inhalers: monitor for reduced bronchodilation effect.

Frequently asked questions

What is Kivizidiale used for?+
Kivizidiale is a prescription ophthalmic solution that combines timolol and travoprost to lower intra‑ocular pressure in patients with primary open‑angle glaucoma or ocular hypertension, helping to prevent optic nerve damage and preserve vision.
How does the combination of timolol and travoprost work?+
Timolol reduces the production of aqueous humor by blocking β‑adrenergic receptors in the eye, while travoprost increases the outflow of fluid through the uveoscleral pathway as a prostaglandin analog. Together they provide a synergistic pressure‑lowering effect.
What is the usual dose of Kivizidiale?+
The dosing regimen for Kivizidiale is determined by the prescribing ophthalmologist based on the individual patient's condition, response, and tolerance. Patients should follow the specific instructions provided by their healthcare professional.
Is Kivizidiale safe during pregnancy or breastfeeding?+
Safety of Kivizidiale in pregnancy or lactation has not been fully established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by a qualified clinician.
How do I order Kivizidiale from GNH USA?+
To order Kivizidiale, submit an enquiry on the product page at gnh-usa.com with the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Kivizidiale compare with other glaucoma treatments?+
Compared with single‑agent therapies, the timolol‑travoprost combination offers dual mechanisms—decreased fluid production and increased outflow—resulting in greater intra‑ocular pressure reduction. This can be advantageous over monotherapy when target pressure is not achieved with a single drug.
What are the storage requirements for Kivizidiale?+
Store Kivizidiale at room temperature, preferably below 25 °C. Keep the bottle in its original packaging, protect it from light and moisture, and ensure the cap is tightly closed to maintain sterility.
How is Kivizidiale administered?+
Kivizidiale is applied as an eye drop. The patient should wash their hands, tilt the head back, pull down the lower eyelid, and instill the prescribed number of drops into the conjunctival sac, avoiding contact between the tip and the eye.
What are the most serious risks associated with Kivizidiale?+
Serious risks include severe allergic reactions, significant eyelid swelling, persistent eye pain, sudden vision loss, and systemic beta‑blocker effects such as bradycardia, hypotension, or bronchospasm, especially in patients with pre‑existing cardiovascular or respiratory conditions.
Who should not use Kivizidiale?+
Kivizidiale should be avoided in patients with known hypersensitivity to timolol, travoprost, or any excipients, as well as those with severe asthma, chronic obstructive pulmonary disease, sinus bradycardia, second‑ or third‑degree heart block, or uncontrolled heart failure unless specifically directed by a physician.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Timolol, Travoprost
Route
Ocular Use
Manufacturer
Bausch + Lomb Ireland Limited
Origin
EU

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