GNH USA

Europe — EMA

Kivizidiale

GNH USA supplies Kivizidiale (Timolol/Travoprost), a beta blocker/prostaglandin analog combination for primary open-angle glaucoma and ocular hypertension.

Timolol, Travoprost

Request sourcing

1
Pack/s

What is Timolol, Travoprost?

Timolol, the active ingredient in Kivizidiale, is a beta blocker/prostaglandin analog combination presented as a eye drops for ocular use. It treats primary open-angle glaucoma and ocular hypertension.\n\nGNH India supplies Kivizidiale as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Timolol, Travoprost used for?

Kivizidiale is indicated for conditions involving elevated intra‑ocular pressure within the glaucoma and ocular hypertension disease family.\n\nPrimary open-angle glaucoma: reduces intra‑ocular pressure to slow optic nerve damage.\nOcular hypertension: lowers intra‑ocular pressure to prevent progression to glaucoma.

What are the side effects of Timolol, Travoprost?

Kivizidiale may cause ocular and systemic adverse reactions.\n\nCommon Side Effects:\n- Eye irritation or burning sensation\n- Transient blurred vision\n- Conjunctival hyperemia\n- Increased eyelash growth\n\nSerious or Rare Side Effects:\n- Severe allergic reaction (e.g., angio‑edema)\n- Bronchospasm or worsening asthma\n- Marked bradycardia or systemic hypotension

What precautions apply to Timolol, Travoprost?

Before prescribing Kivizidiale, clinicians should consider several safety aspects.\n\nAssess cardiovascular status: evaluate patients with severe bradycardia or heart block.\nMonitor respiratory conditions: use caution in individuals with asthma or COPD.\nCheck for sulfonamide allergy: avoid if known hypersensitivity exists.\nAvoid use in patients with narrow-angle glaucoma.\nPregnancy and lactation: safety not established; use only if benefit outweighs risk.\nStore at room temperature: keep in original container, protect from light and moisture.

What does Timolol, Travoprost interact with?

Kivizidiale can interact with other medicines, requiring attention to potential additive effects.\n\nMajor Interactions (Avoid):\n- Non‑selective beta‑blockers (e.g., propranolol): risk of additive bradycardia or hypotension.\n- Other intra‑ocular pressure‑lowering agents (e.g., apraclonidine): may cause excessive ocular hypotension.\n- Sympathomimetic eye drops (e.g., epinephrine): may diminish timolol efficacy.\n\nModerate Interactions (Monitor Closely):\n- Systemic carbonic anhydrase inhibitors: possible additive IOP reduction.\n- Anticholinergic eye drops: may affect ocular surface tolerance.\n- MAO inhibitors: monitor for systemic cardiovascular effects.

Frequently asked questions

What is Kivizidiale used for?+
Kivizidiale is a prescription eye‑drop formulation that combines timolol and travoprost to lower intra‑ocular pressure. It is used primarily in the management of primary open‑angle glaucoma and ocular hypertension, helping to prevent optic nerve damage and preserve visual function.
How does Timolol/Travoprost work?+
Timolol reduces the production of aqueous humor by blocking β‑adrenergic receptors in the eye, while travoprost, a prostaglandin F2α analogue, increases uveoscleral outflow of aqueous humor. The dual mechanism results in a net decrease in intra‑ocular pressure.
What is the usual dose of Kivizidiale?+
The specific dosing regimen for Kivizidiale is determined by the prescribing clinician. Typically, one drop is instilled in the affected eye(s) once daily, but the exact dose and frequency should follow the healthcare professional’s instructions.
Is Kivizidiale safe in pregnancy or breastfeeding?+
Safety data for Kivizidiale during pregnancy and lactation are limited. It should only be used when the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.
How do I order Kivizidiale from GNH USA?+
To order Kivizidiale, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Kivizidiale compare with other antiglaucoma agents?+
Kivizidiale combines a beta‑blocker and a prostaglandin analogue in a single formulation, offering the IOP‑lowering benefits of both classes. Compared with monotherapy agents, the combination can achieve greater pressure reduction, potentially simplifying treatment regimens for patients who need dual‑mechanism therapy.
How should Kivizidiale be stored and handled?+
Kivizidiale eye drops should be stored at room temperature, away from direct sunlight and moisture. Keep the bottle tightly closed in its original packaging until use, and discard any solution that appears discolored or contaminated.
How is Kivizidiale administered?+
Kivizidiale is administered topically to the eye. The usual method is to instill one drop into the prescribed eye(s) using the provided dropper, taking care not to touch the tip of the bottle to the ocular surface or any other object.
What are the most serious risks to watch for?+
Serious adverse events associated with Kivizidiale include severe allergic reactions such as angio‑edema, bronchospasm or worsening asthma, marked bradycardia, systemic hypotension, and rare ocular changes like iris pigmentation or periorbital fat atrophy. Patients should seek immediate medical attention if these occur.
Who should not use Kivizidiale?+
Kivizidiale should be avoided in individuals with known hypersensitivity to timolol, travoprost or any excipients, patients with severe asthma or chronic obstructive pulmonary disease, those with sinus bradycardia or heart block, and persons with narrow‑angle glaucoma.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Timolol, Travoprost
Route
Ocular Use
Manufacturer
Bausch + Lomb Ireland Limited
Origin
EU

Related products