Kinox

Ciprofloxacin, the active ingredient in Kinox, is a fluoroquinolone presented as a tablet for oral use. It treats a range of bacterial infections in adults and children when prescribed by a healthcare professional.

GNH USA supplies Kinox as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ciprofloxacin is a fluoroquinolone antibacterial that interferes with bacterial DNA synthesis, making it effective for several infection types. - Urinary tract infections: eradicates susceptible uropathogens and alleviates urinary symptoms. - Respiratory tract infections: treats community‑acquired pneumonia and bronchitis caused by susceptible bacteria. - Skin and soft tissue infections: clears cellulitis, abscesses and wound infections. - Gastrointestinal infections: combats bacterial gastroenteritis and travel‑related diarrhoea. - Sexually transmitted infections: effective against gonorrhoea and other susceptible organisms.

Ciprofloxacin may cause a variety of adverse reactions, ranging from mild to severe.

Common Side Effects: - Nausea or vomiting - Diarrhoea - Headache - Dizziness - Abdominal pain - Rash or mild skin irritation

Serious or Rare Side Effects: - Tendon rupture or inflammation, especially in the Achilles tendon - Peripheral neuropathy with sensory changes - Severe allergic reactions such as anaphylaxis - QT interval prolongation leading to cardiac arrhythmias - Clostridioides difficile‑associated colitis - Central nervous system effects like seizures or hallucinations

Ciprofloxacin should be used with caution and under medical supervision. - Renal impairment: dose adjustment may be required based on kidney function. - Hepatic disease: monitor liver enzymes and adjust therapy if needed. - History of tendon disorders: avoid use in patients with prior tendon injury or those on corticosteroids. - QT prolongation risk: avoid in patients with known cardiac conduction abnormalities. - Pregnancy and breastfeeding: only use if the potential benefit outweighs the risk, after professional evaluation. - Store at room temperature below 25°C: keep in the original packaging, protect from moisture.

Ciprofloxacin can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid): - Antacids containing aluminium or magnesium: markedly reduce ciprofloxacin absorption. - Warfarin: may increase anticoagulant effect and bleeding risk. - Theophylline: can raise serum theophylline levels, leading to toxicity.

Moderate Interactions (Monitor Closely): - Non‑steroidal anti‑inflammatory drugs (NSAIDs): may increase risk of CNS stimulation. - Corticosteroids: combined use may raise tendon rupture risk. - Diabetic agents (e.g., insulin, sulfonylureas): ciprofloxacin may enhance hypoglycaemic effects.