GNH USA

Europe — EMA

Kinofta

GNH USA supplies Kinofta (Levofloxacin), a fluoroquinolone antibiotic for bacterial eye infections such as conjunctivitis and keratitis. Request a quote.

Levofloxacin Hemihydrate

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What is Levofloxacin Hemihydrate?

Levofloxacin, the active ingredient in Kinofta, is a fluoroquinolone presented as an ophthalmic preparation for ocular use. It treats bacterial eye infections, including conjunctivitis and keratitis, in patients requiring topical antibiotic therapy.

GNH USA supplies Kinofta as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable sourcing for qualified healthcare providers.

What is Levofloxacin Hemihydrate used for?

Kinofta, containing levofloxacin, is employed in the management of bacterial ocular infections.

- Bacterial conjunctivitis: reduces bacterial load and accelerates resolution of redness and discharge. - Bacterial keratitis: eradicates causative organisms and promotes corneal healing. - Post‑operative ocular prophylaxis: prevents infection after eye surgery such as cataract extraction. - Contact lens‑related infections: treats bacterial contamination associated with lens wear.

What are the side effects of Levofloxacin Hemihydrate?

Ocular administration of levofloxacin may be associated with a range of local and systemic adverse reactions.

Common Side Effects: - Eye irritation: mild burning or stinging upon instillation. - Redness: transient conjunctival hyperemia. - Tearing: increased lacrimation. - Foreign body sensation: feeling of grit in the eye. - Blurred vision: temporary visual disturbance.

Serious or Rare Side Effects: - Allergic reaction: swelling, itching, or rash around the eye. - Corneal ulceration: worsening of corneal integrity. - Stevens‑Johnson syndrome: severe mucocutaneous reaction. - Vision loss: sudden decrease in visual acuity. - Severe ocular inflammation: uveitis or endophthalmitis.

What precautions apply to Levofloxacin Hemihydrate?

Before using Kinofta, consider the following precautions to ensure safe and effective therapy. - Allergy assessment: avoid use in patients with known hypersensitivity to fluoroquinolones. - Corneal integrity: do not use on compromised corneal epithelium without medical supervision. - Contact lens wearers: remove lenses before instillation and wait before reinserting. - Systemic absorption: monitor for systemic fluoroquinolone effects in children and the elderly. - Pregnancy and lactation: use only if the potential benefit outweighs the unknown risk. - Store at room temperature: keep in the original container, protect from moisture and light.

What does Levofloxacin Hemihydrate interact with?

Levofloxacin may interact with other medications, altering its efficacy or safety profile.

Major Interactions (Avoid): - Systemic fluoroquinolones: concurrent use can increase risk of systemic toxicity. - Antacids containing magnesium or aluminum: may reduce ocular absorption if administered simultaneously. - Warfarin: may potentiate anticoagulant effect, increasing bleeding risk.

Moderate Interactions (Monitor Closely): - Corticosteroid eye drops: combined use may heighten risk of corneal perforation. - Non‑steroidal anti‑inflammatory drugs (NSAIDs): monitor for delayed wound healing. - Diabetes medications: observe for potential alterations in glycemic control.

Frequently asked questions

What is Kinofta used for?+
Kinofta is a levofloxacin‑based ophthalmic preparation indicated for the treatment of bacterial eye infections. It is commonly prescribed for conditions such as bacterial conjunctivitis, keratitis, and as prophylaxis following ocular surgery to prevent infection.
How does levofloxacin work?+
Levofloxacin blocks bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. Inhibiting these enzymes stops bacterial cell division and leads to bacterial death, providing a bactericidal effect against a broad range of ocular pathogens.
What determines the dose of Kinofta?+
The dosage and frequency of Kinofta are determined by the prescribing clinician based on the specific infection, severity, and patient factors. The product label provides guidance, but the final regimen is set by the healthcare professional.
Is Kinofta safe during pregnancy or breastfeeding?+
Safety data for levofloxacin in pregnancy and lactation are limited. Use is only recommended when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision should be made by the prescriber.
How do I order Kinofta from GNH USA?+
To order Kinofta, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Kinofta compare with other ocular antibiotics?+
Kinofta (levofloxacin) offers a broad spectrum of activity similar to other fluoroquinolone eye drops such as moxifloxacin or ciprofloxacin. Compared with older agents, levofloxacin often provides higher potency against resistant strains, but choice depends on local resistance patterns and physician preference.
How should Kinofta be stored and handled?+
Kinofta should be stored at room temperature, below 25 °C, in its original container. Protect the product from moisture and direct light. Do not freeze. Keep the vial tightly closed when not in use.
How is Kinofta administered?+
Kinofta is applied as eye drops. The recommended technique is to wash hands, tilt the head back, pull down the lower eyelid, and instill the prescribed number of drops into the conjunctival sac. Avoid touching the dropper tip to any surface.
What are the most serious risks associated with Kinofta?+
Serious adverse reactions can include allergic eye inflammation, corneal ulceration, Stevens‑Johnson syndrome, and sudden loss of vision. Patients should seek immediate medical attention if they experience severe eye pain, swelling, or visual changes after using the drops.
Who should not use Kinofta?+
Kinofta should not be used by individuals with a known hypersensitivity to levofloxacin or other fluoroquinolones. It is also contraindicated on severely damaged corneal epithelium without supervision, and caution is advised in pregnant or nursing women when benefits do not clearly outweigh risks.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Levofloxacin Hemihydrate
Route
Ocular Use
Manufacturer
Offhealth S.P.A.
Origin
EU

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