GNH USA

Europe — EMA

Kilspax

GNH USA supplies Kilspax (Phloroglucinol), a muscle relaxant for abdominal pain, biliary colic, renal colic and menstrual cramps. Request a quote for supply.

Phloroglucinol Dihydrate

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Pack/s

What is Phloroglucinol Dihydrate?

Phloroglucinol, the active ingredient in Kilspax, is an antispasmodic presented as an oral dosage form for oral use. It helps relieve smooth‑muscle spasms that cause abdominal pain, biliary colic, renal colic and menstrual cramps in adult patients, and is indicated for use in both acute and recurrent episodes.

GNH USA supplies Kilspax as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable sourcing, regulatory support and global logistics for consistent product availability and ensures compliance with EU pharmacopeial standards.

What is Phloroglucinol Dihydrate used for?

Kilspax (phloroglucinol) acts as a smooth‑muscle relaxant to alleviate spasm‑related conditions.

Abdominal pain: reduces painful intestinal spasms, improving comfort. Biliary colic: relaxes biliary smooth muscle, facilitating bile flow and relieving colicky pain. Renal colic: eases ureteral smooth‑muscle spasm, helping to diminish flank pain. Menstrual cramps: diminishes uterine muscle contractions, decreasing dysmenorrhea severity.

What are the side effects of Phloroglucinol Dihydrate?

Phloroglucinol may be associated with several adverse reactions, most of which are mild and reversible.

Common Side Effects: - Nausea - Dizziness - Headache - Dry mouth - Abdominal discomfort - Diarrhoea

Serious or Rare Side Effects: - Allergic reactions (rash, urticaria) - Severe hypotension - Hepatic enzyme elevation - Anaphylaxis - Severe neutropenia

What precautions apply to Phloroglucinol Dihydrate?

Before prescribing Kilspax, clinicians should consider the following precautions.

Assess renal function: adjust use in severe renal impairment. Avoid in known hypersensitivity to phloroglucinol. Use caution in patients with hepatic disease. Monitor for signs of allergic reaction during initial therapy. Store below 25°C: keep in the original pack, protect from moisture.

What does Phloroglucinol Dihydrate interact with?

Potential drug interactions should be reviewed prior to initiating therapy.

Major Interactions (Avoid): - Concurrent use with other antispasmodics: additive muscle relaxation may cause severe hypotension. - Combination with potent CYP inhibitors: may increase plasma levels of phloroglucinol.

Moderate Interactions (Monitor Closely): - Co‑administration with antihypertensives: may enhance blood‑pressure‑lowering effect. - Use with diuretics: monitor electrolyte balance. - Concurrent use with drugs that prolong QT interval: monitor cardiac rhythm.

Frequently asked questions

What is Kilspax used for?+
Kilspax contains phloroglucinol and is used to relieve smooth‑muscle spasms that cause abdominal pain, biliary colic, renal colic and menstrual cramps. It is prescribed for adults experiencing acute or recurrent episodes of these spasm‑related conditions.
How does phloroglucinol work?+
Phloroglucinol works by blocking calcium entry into smooth‑muscle cells, which lowers intracellular calcium levels and prevents muscle contraction. This direct action relaxes the smooth muscle of the gastrointestinal, biliary, urinary and uterine tracts, reducing spasm‑induced discomfort.
What is the usual dose of Kilspax?+
The dosage of Kilspax is determined by the prescribing healthcare professional based on the patient’s condition, severity of symptoms and individual response. Patients should follow the exact regimen provided by their prescriber and not adjust the dose on their own.
Is Kilspax safe during pregnancy or breastfeeding?+
Safety data for phloroglucinol in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and only under medical supervision.
How do I order Kilspax from GNH USA?+
To request Kilspax, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Kilspax compare with other antispasmodics?+
Kilspax (phloroglucinol) is a direct smooth‑muscle relaxant that does not possess anticholinergic activity, unlike agents such as hyoscine butylbromide. This can result in fewer anticholinergic side effects such as dry mouth or blurred vision, while providing comparable relief of spasm‑related pain.
How should Kilspax be stored and handled?+
Kilspax should be stored below 25 °C, in its original packaging, protected from moisture and direct sunlight. Keep the product out of reach of children and avoid exposing it to excessive heat or humidity to maintain its stability.
How is Kilspax administered?+
Kilspax is taken orally, usually with a glass of water. It can be taken with or without food, unless the prescriber advises otherwise. Swallow the tablet whole; do not crush or chew unless instructed by a healthcare professional.
What are the most serious risks associated with Kilspax?+
The most serious risks include severe allergic reactions such as rash, urticaria or anaphylaxis, and marked hypotension that may lead to dizziness or fainting. Patients should seek immediate medical attention if they experience any signs of a severe reaction.
Who should not use Kilspax?+
Kilspax should be avoided in individuals with known hypersensitivity to phloroglucinol or any of its excipients, and in patients with severe renal or hepatic impairment unless specifically directed by a physician. Caution is also advised for those taking multiple antispasmodic agents.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Phloroglucinol Dihydrate
Route
Oral Use
Manufacturer
Velit Biopharma S.R.L
Origin
EU

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