GNH USA

Europe — EMA

Kidofen

GNH USA supplies Kidofen (Ibuprofen), a nonsteroidal anti-inflammatory drug for pain, fever and inflammation.

Ibuprofen

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What is Ibuprofen?

Ibuprofen, the active ingredient in Kidofen, is a nonsteroidal anti-inflammatory drug (NSAID) presented as a suppository for rectal use. It treats pain, fever, inflammation and dysmenorrhea in children and adults as appropriate.

GNH USA supplies Kidofen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Ibuprofen used for?

Ibuprofen, an NSAID, reduces inflammation and pain by inhibiting cyclooxygenase enzymes.

- Pain: provides relief of mild to moderate pain. - Fever: lowers elevated body temperature. - Inflammation: diminishes swelling and inflammatory discomfort. - Dysmenorrhea: eases menstrual cramps and associated pain.

What are the side effects of Ibuprofen?

Kidofen may cause a range of adverse reactions. Most are mild and reversible.

Common Side Effects: - Abdominal discomfort. - Nausea or mild vomiting. - Headache. - Local rectal irritation.

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulceration. - Severe allergic reaction (anaphylaxis). - Kidney function impairment.

What precautions apply to Ibuprofen?

Before using Kidofen, consider the following precautions.

- Allergy assessment: avoid if known hypersensitivity to ibuprofen or other NSAIDs. - Dose minimisation: use the lowest effective amount for the shortest duration. - Ulcer risk: do not use in patients with active peptic ulcer disease. - Renal monitoring: exercise caution in dehydration or existing kidney impairment. - Anticoagulant caution: assess bleeding risk when combined with anticoagulants. - Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

What does Ibuprofen interact with?

Kidofen can interact with several medicines; monitoring is advised.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin) – increased bleeding risk. - Other NSAIDs or aspirin – additive gastrointestinal toxicity. - Corticosteroids – heightened risk of ulceration.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs – possible decline in renal function. - SSRIs – may increase bleeding tendency.

Frequently asked questions

What is Kidofen used for?+
Kidofen is an ibuprofen‑based rectal suppository indicated for the temporary relief of mild to moderate pain, reduction of fever, and mitigation of inflammation, including menstrual (dysmenorrhea) discomfort. It is an over‑the‑counter NSAID commonly employed when oral administration is not feasible or preferred.
How does ibuprofen work?+
Ibuprofen exerts its effect by non‑selectively inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes. This inhibition blocks the synthesis of prostaglandins, which are mediators of inflammation, pain, and fever, thereby providing analgesic, antipyretic, and anti‑inflammatory actions.
What is the usual dose of Kidofen?+
The appropriate dose of Kidofen is determined by a qualified healthcare professional based on the patient’s age, weight, clinical condition, and response to therapy. Patients should follow the prescriber’s instructions and the product labeling without exceeding the recommended amount.
Is Kidofen safe during pregnancy or breastfeeding?+
The safety of ibuprofen suppositories during pregnancy and lactation has not been definitively established. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their physician before using Kidofen to weigh potential risks and benefits.
How do I order Kidofen from GNH USA?+
To place an order, submit an enquiry on the Kidofen product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.
How does Kidofen compare with other NSAIDs?+
Kidofen delivers ibuprofen, a widely used NSAID with a well‑characterised safety profile. Compared with naproxen, ibuprofen has a shorter half‑life, allowing more flexible dosing, while offering similar analgesic and anti‑inflammatory efficacy. Unlike acetaminophen, ibuprofen also provides anti‑inflammatory action but carries a higher risk of gastrointestinal irritation.
How should Kidofen be stored and handled?+
Kidofen suppositories should be stored at room temperature, below 25 °C, in their original blister pack to protect them from moisture and direct sunlight. Keep the product out of reach of children and avoid storing in bathrooms or other humid environments.
How is Kidofen administered?+
Kidofen is inserted rectally. The user should wash hands, remove the suppository from its packaging, and gently insert it into the rectum, preferably after a bowel movement. The suppository melts at body temperature, delivering ibuprofen systemically.
What are the most serious risks to watch for when using Kidofen?+
Serious adverse events, although uncommon, include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, and impaired kidney function. Patients should seek immediate medical attention if they experience black stools, vomiting blood, rash, swelling of the face or throat, or sudden decrease in urine output.
Who should not use Kidofen?+
Kidofen should be avoided by individuals with known hypersensitivity to ibuprofen or any NSAID, those with active peptic ulcer disease, severe heart failure, uncontrolled hypertension, or significant renal or hepatic impairment unless directed by a physician. It is also contraindicated in patients taking anticoagulants without medical supervision.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Ibuprofen
Route
Rectal Use
Manufacturer
Aflofarm Farmacja Polska Sp. Z O.O.
Origin
EU

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