GNH USA

Europe — EMA

Kidofen Duo

GNH USA supplies Kidofen Duo (Ibuprofen/Paracetamol), a combination NSAID/analgesic for pain relief and fever reduction. Request a quote for global supply.

Ibuprofen, Paracetamol

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What is Ibuprofen, Paracetamol?

Ibuprofen and Paracetamol, the active ingredients in Kidofen Duo, are a combination NSAID/Analgesic presented as an oral tablet for oral use. They provide pain relief and fever reduction in children and adults requiring dual-action therapy. It is commonly employed for short‑term management of mild to moderate discomfort.

GNH USA supplies Kidofen Duo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution across regions.

What is Ibuprofen, Paracetamol used for?

Kidofen Duo, a combination NSAID/analgesic, is indicated for conditions where pain or fever are present.

- Pain relief: alleviates mild to moderate pain such as headache, toothache or postoperative discomfort. - Fever reduction: lowers elevated body temperature in febrile states. - Headache: provides rapid relief of tension‑type or mild migraine pain. - Musculoskeletal pain: eases discomfort associated with strains, sprains or arthritis.

What are the side effects of Ibuprofen, Paracetamol?

Kidofen Duo may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects: - Gastrointestinal discomfort: nausea, dyspepsia, or mild abdominal pain that usually resolves without treatment. - Headache: transient headache may occur, often mild and self‑limiting. - Dizziness: occasional light‑headedness or vertigo, typically short‑lasting. - Skin rash: mild erythematous rash or itching, generally reversible after discontinuation.

Serious or Rare Side Effects: - Gastrointestinal bleeding: ulceration or hemorrhage that can present as black stools or vomiting blood. - Severe allergic reaction: anaphylaxis, facial swelling, hives, or bronchospasm requiring immediate medical attention. - Hepatotoxicity: elevated liver enzymes or clinically significant liver injury, especially with overdose or chronic use. - Renal impairment: acute kidney injury, particularly in patients with dehydration or pre‑existing renal disease.

What precautions apply to Ibuprofen, Paracetamol?

When using Kidofen Duo, several precautions should be observed to ensure safe administration.

- Assess renal function: evaluate kidney status before use, especially in patients with chronic renal disease. - Avoid in known hypersensitivity: do not use if the patient has allergy to ibuprofen, paracetamol or any excipients. - Limit concurrent alcohol intake: alcohol may increase risk of liver injury and gastrointestinal irritation. - Monitor liver enzymes: prolonged high‑dose therapy may affect hepatic function, requiring periodic testing. - Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

What does Ibuprofen, Paracetamol interact with?

Kidofen Duo can interact with other medicines; awareness of major and moderate interactions helps prevent adverse outcomes.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of bleeding. - Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity. - High‑dose corticosteroids: heightened ulcer risk. - Methotrexate: reduced clearance leading to toxicity.

Moderate Interactions (Monitor Closely): - Diuretics: may reduce renal perfusion, increasing risk of kidney injury. - ACE inhibitors or ARBs: possible decline in renal function when combined. - Lithium: increased serum lithium levels, risk of toxicity. - Alcohol: enhanced hepatotoxic potential.

Frequently asked questions

What is Kidofen Duo used for?+
Kidofen Duo is a fixed‑dose combination of ibuprofen and paracetamol used to relieve mild to moderate pain and to reduce fever. It is commonly prescribed for conditions such as headache, toothache, musculoskeletal discomfort, and febrile illnesses in both children and adults.
How does the active ingredients in Kidofen Duo work?+
Ibuprofen blocks cyclo‑oxygenase enzymes, lowering prostaglandin production and thereby reducing inflammation, pain, and fever. Paracetamol works mainly in the central nervous system, inhibiting COX activity and influencing serotonergic pathways to provide analgesic and antipyretic effects. Together they offer complementary pain and fever control.
What is the usual dose of Kidofen Duo?+
The appropriate dose of Kidofen Duo is determined by a qualified healthcare professional based on the patient’s age, weight, clinical condition, and other medications. Prescribers set the regimen to achieve optimal benefit while minimizing risk, and patients should follow the specific instructions provided on the prescription label.
Is Kidofen Duo safe during pregnancy or breastfeeding?+
Safety data for the combined use of ibuprofen and paracetamol during pregnancy or lactation are limited. Paracetamol is generally considered compatible with short‑term use, whereas ibuprofen is usually avoided in the third trimester. Women who are pregnant, planning pregnancy, or breastfeeding should consult their physician before using Kidofen Duo.
How do I order Kidofen Duo from GNH USA?+
To order Kidofen Duo, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.
How does Kidofen Duo compare with single‑ingredient ibuprofen or paracetamol?+
Kidofen Duo combines the anti‑inflammatory properties of ibuprofen with the central analgesic and antipyretic actions of paracetamol. This dual mechanism can provide broader symptom control and may allow lower individual doses compared with using either agent alone, potentially reducing dose‑related side effects while maintaining efficacy.
How should Kidofen Duo be stored and handled?+
Kidofen Duo should be stored at room temperature, below 25 °C, in its original container to protect it from moisture and direct sunlight. Keep the product out of reach of children and avoid exposing it to excessive heat or humidity, which could affect tablet integrity.
How is Kidofen Duo administered?+
Kidofen Duo is taken orally, usually with a full glass of water. It can be taken with or without food, although taking it with food may lessen gastrointestinal discomfort. The exact timing and frequency should follow the prescribing clinician’s instructions.
What are the most serious risks associated with Kidofen Duo?+
Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, hepatotoxicity (liver injury), and acute kidney injury, especially when used in high doses, with dehydration, or in patients with pre‑existing organ dysfunction. Prompt medical attention is required if any of these events occur.
Who should not use Kidofen Duo?+
Kidofen Duo should be avoided in individuals with known hypersensitivity to ibuprofen, paracetamol, or any formulation excipients. It is also contraindicated in patients with active gastrointestinal bleeding, severe liver disease, severe renal impairment, or in the third trimester of pregnancy unless specifically directed by a physician.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Ibuprofen, Paracetamol
Route
Oral Use
Manufacturer
Aflofarm Farmacja Polska Sp. Z O.O.
Origin
EU

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