Ketotifen Teva

Ketotifen, the active ingredient in Ketotifen Teva, is an antihistamine presented as an oral tablet for oral use. It is employed to relieve symptoms of allergic rhinitis, allergic conjunctivitis, and to aid in asthma prophylaxis, particularly in patients with seasonal or perennial allergies.

GNH USA supplies Ketotifen Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable sourcing for global healthcare providers, including regulatory documentation and pharmacovigilance support.

Ketotifen is an antihistamine used in the management of allergic and asthmatic conditions.

- Allergic rhinitis: reduces nasal congestion, sneezing, itching and watery discharge. - Allergic conjunctivitis: alleviates eye itching, redness, swelling and tearing. - Asthma prophylaxis: helps prevent bronchospasm and airway inflammation in mild to moderate asthma.

Ketotifen is generally well tolerated, but several adverse reactions have been reported.

Common Side Effects: - Drowsiness or somnolence. - Dry mouth or throat. - Headache. - Dizziness or light‑headedness. - Nausea or mild gastrointestinal upset. - Weight gain or increased appetite.

Serious or Rare Side Effects: - Severe skin reactions such as Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Hepatotoxicity or abnormal liver function tests. - Hematologic abnormalities including agranulocytosis or thrombocytopenia. - Anaphylactic or anaphylactoid reactions. - Cardiac arrhythmias in susceptible individuals. - Persistent or worsening asthma symptoms despite therapy.

Ketotifen should be used with caution and under medical supervision.

- Pregnancy: discuss potential risks with a healthcare professional before use. - Breastfeeding: evaluate benefits versus possible infant exposure. - Driving or operating machinery: avoid activities requiring alertness if drowsiness occurs. - Concomitant CNS depressants: monitor for additive sedation. - Pre‑existing liver disease: assess liver function prior to initiation. - Store at ambient temperature: keep below 25 °C in the original packaging, protect from moisture and direct sunlight.

Ketotifen may interact with several medicines, requiring attention to dosage and monitoring.

Major Interactions (Avoid): - Monoamine oxidase inhibitors (MAOIs): risk of exaggerated antihistaminic effects. - CNS depressants (e.g., benzodiazepines, opioids): may cause excessive sedation or respiratory depression. - Anticholinergic agents: increase risk of dry mouth and constipation.

Moderate Interactions (Monitor Closely): - CYP450 inhibitors (e.g., erythromycin, fluconazole): may raise ketotifen plasma levels. - CYP450 inducers (e.g., rifampicin, carbamazepine): may reduce therapeutic effect. - Other antihistamines: additive anticholinergic or sedative effects.