Europe — EMA
Ketotifen Al
GNH USA supplies Ketotifen Al (Ketotifen), a antihistamine for allergic rhinitis, allergic conjunctivitis and asthma prophylaxis. Request a quote for supply.
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What is Ketotifen Hydrogen Fumarate?
Ketotifen, the active ingredient in Ketotifen Al, is an antihistamine presented as a tablet for oral use. It alleviates symptoms of allergic rhinitis, allergic conjunctivitis, and serves as prophylaxis for asthma in patients with allergic triggers. It is indicated for both seasonal and perennial allergy manifestations and is commonly prescribed for children and adults.
GNH USA supplies Ketotifen Al as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to Good Distribution Practice, ensures product integrity, and provides regulatory documentation to support import across EU and other markets.
What is Ketotifen Hydrogen Fumarate used for?
Ketotifen is an H1‑receptor antagonist used in the management of allergic conditions.
Allergic rhinitis: reduces nasal congestion, sneezing, itching and rhinorrhea associated with seasonal or perennial allergies. Allergic conjunctivitis: alleviates eye itching, redness, tearing and swelling caused by allergen exposure. Asthma prophylaxis: helps prevent exercise‑induced and allergen‑triggered bronchospasm in patients with allergic asthma.
What are the side effects of Ketotifen Hydrogen Fumarate?
Ketotifen may cause a range of adverse reactions, varying from mild to serious.
Common Side Effects: - Drowsiness or fatigue - Dry mouth - Headache - Dizziness - Nausea
Serious or Rare Side Effects: - Stevens‑Johnson syndrome or severe skin reactions - Hepatic dysfunction or elevated liver enzymes - Cardiac arrhythmias - Anaphylactic reactions - Severe bronchospasm in susceptible individuals
What precautions apply to Ketotifen Hydrogen Fumarate?
When prescribing ketotifen, clinicians should consider several safety measures.
Assess patient history: identify prior hypersensitivity to antihistamines. Monitor sedation: advise caution when operating machinery or driving. Avoid use in narrow‑angle glaucoma: may increase intra‑ocular pressure. Consider hepatic impairment: dose adjustment may be required. Pregnancy and lactation: use only if benefit outweighs risk, as safety data are limited. Store at ambient temperature: keep below 25 °C, in original container, protect from moisture and light.
What does Ketotifen Hydrogen Fumarate interact with?
Ketotifen can interact with other medicines, altering efficacy or safety.
Major Interactions (Avoid): - CNS depressants: additive sedation and impaired alertness. - Monoamine oxidase inhibitors: risk of exaggerated antihistaminic effects. - Strong anticholinergic agents: increased dry mouth and urinary retention.
Moderate Interactions (Monitor Closely): - Theophylline: may reduce bronchodilator response. - β‑agonists: potential antagonism of bronchodilation. - Warfarin: possible alteration of INR and bleeding risk.
Frequently asked questions
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Product details
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