Ketospray

Ketoprofen, the active ingredient in Ketospray, is a nonsteroidal anti-inflammatory drug presented as a topical spray for topical use. It relieves pain and inflammation in musculoskeletal conditions.

GNH USA supplies Ketospray as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ketoprofen is an NSAID that acts on the cyclo‑oxygenase pathway to reduce inflammation and pain. - Osteoarthritis of the knee: provides local pain relief and improves joint function. - Acute muscle sprain or strain: diminishes swelling and eases movement. - Tendinitis and bursitis: reduces localized inflammation and discomfort. - Rheumatoid arthritis flare‑ups (topical adjunct): helps control peripheral joint pain when used with systemic therapy.

Ketoprofen may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects: - Skin irritation at the application site: redness or itching. - Localized burning or stinging sensation. - Dryness or peeling of the treated skin. - Mild headache. - Gastro‑intestinal discomfort (rare with topical use).

Serious or Rare Side Effects: - Severe allergic reaction: hives, swelling, or difficulty breathing. - Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Significant liver enzyme elevation. - Renal function impairment in susceptible patients.

Ketoprofen should be used with awareness of its safety profile and patient‑specific factors. - Contraindication: avoid in patients with known hypersensitivity to ketoprofen or other NSAIDs. - Caution: use carefully in individuals with a history of asthma, urticaria, or allergic reactions to NSAIDs. - Pregnancy: not recommended during the third trimester; consult a healthcare professional. - Breastfeeding: discuss risks with a physician, as small amounts may be excreted in milk. - Drug interactions: review concomitant medications for potential NSAID‑related risks. - Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Ketoprofen can affect the safety or efficacy of several other medicines.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of serious bleeding. - Other NSAIDs or COX‑2 inhibitors: heightened gastrointestinal toxicity. - High‑dose aspirin: additive renal and gastrointestinal adverse effects.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: possible reduction in antihypertensive effect and renal function changes. - Diuretics: may enhance renal impairment risk. - Lithium: NSAIDs can raise lithium serum concentrations.