Ketospray

Ketoprofen, the active ingredient in Ketospray, is a nonsteroidal anti‑inflammatory drug (NSAID) presented as a topical spray for cutaneous application. It works by reducing prostaglandin synthesis, providing relief from mild to moderate musculoskeletal pain, joint inflammation, and localized soft‑tissue discomfort in adult patients.

GNH USA supplies Ketospray as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches to meet global demand across multiple regions and therapeutic areas.

Ketoprofen is indicated for conditions involving inflammation and pain in the musculoskeletal system.

- Mild to moderate musculoskeletal pain: Reduces pain and improves function in conditions such as backache or overuse injuries. - Arthritic joint inflammation: Alleviates swelling and discomfort associated with osteoarthritis and rheumatoid arthritis. - Localized soft‑tissue injuries: Provides topical relief for sprains, strains, and bruises.

Ketoprofen may cause adverse reactions, which are generally classified by frequency and severity.

Common Side Effects: - Skin irritation at application site: redness, itching, or burning sensation. - Localized itching or rash. - Dryness of the skin. - Mild headache.

Serious or Rare Side Effects: - Severe allergic reaction: swelling of face, lips, or throat, and difficulty breathing. - Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Significant gastrointestinal bleeding (rare with topical use).

When using Ketospray, certain precautions should be observed to minimize risks and ensure optimal therapeutic outcomes.

- Avoid application on broken or infected skin: limit use to intact epidermis. - Do not exceed recommended frequency: follow prescriber instructions for number of applications per day. - Monitor for signs of hypersensitivity: discontinue if rash or swelling develops. - Use with caution in patients with known NSAID sensitivity or asthma. - Keep away from eyes and mucous membranes: avoid accidental contact. - Store at room temperature below 25°C: keep in original container, protect from moisture and direct sunlight.

Ketoprofen can interact with other medicines, affecting its safety or effectiveness.

Major Interactions (Avoid): - Concurrent systemic NSAIDs or COX‑2 inhibitors: increased risk of gastrointestinal ulceration and bleeding. - Anticoagulants (e.g., warfarin): potentiation of bleeding tendency. - Corticosteroids: heightened risk of skin ulceration and systemic adverse effects.

Moderate Interactions (Monitor Closely): - Diuretics (e.g., furosemide): may reduce renal clearance of ketoprofen. - ACE inhibitors or ARBs: possible reduction in renal function, especially in dehydrated patients. - Lithium: NSAIDs may increase lithium serum levels.