Ketorolac S.A.L.F.

Ketorolac Trometamol, the active ingredient in Ketorolac S.A.L.F., is a nonsteroidal anti-inflammatory drug presented as an injectable solution for intramuscular and intravenous use. It is used for short‑term management of moderate to severe acute pain, including post‑operative pain, in adult patients.

GNH USA supplies Ketorolac S.A.L.F. as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Ketorolac Trometamol is an NSAID used to manage pain through cyclooxygenase inhibition.

Acute postoperative pain: provides short‑term relief of moderate to severe pain after surgery. Acute musculoskeletal pain: reduces pain associated with injuries or strains. Renal colic: alleviates severe flank pain caused by kidney stones.

Ketorolac may cause a range of adverse reactions, from mild to severe.

Common Side Effects: - Gastrointestinal discomfort: nausea, dyspepsia, or abdominal pain. - Headache: mild to moderate intensity. - Dizziness: transient sensation of light‑headedness. - Nausea: occasional feeling of queasiness. - Injection site pain: local irritation after intramuscular or intravenous administration. - Mild renal function changes: temporary increase in serum creatinine.

Serious or Rare Side Effects: - Severe gastrointestinal bleeding or ulceration. - Renal impairment or failure, especially with prolonged use. - Anaphylactic or severe hypersensitivity reactions. - Platelet dysfunction leading to abnormal bleeding. - Hepatotoxicity: elevated liver enzymes. - Cardiovascular events such as myocardial infarction or stroke.

Ketorolac requires careful assessment of patient risk factors before use.

Renal function: avoid in patients with severe renal impairment. Bleeding risk: use cautiously in patients with coagulopathy or on anticoagulants. Gastrointestinal ulcer: contraindicated in active ulcer disease. Pregnancy: avoid especially in the third trimester due to fetal risk. Elderly: monitor for renal and central nervous system effects. Store at ambient temperature: keep in original container, protect from light and moisture.

Ketorolac can interact with several drug classes, requiring monitoring or avoidance.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of serious bleeding. - Other NSAIDs or aspirin: additive gastrointestinal toxicity.

Moderate Interactions (Monitor Closely): - ACE inhibitors: may reduce renal function when combined. - Diuretics: heightened risk of renal impairment. - Lithium: potential increase in lithium serum concentrations.