Ketorolac Micro Labs

Ketorolac Trometamol, the active ingredient in Ketorolac Micro Labs, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an ophthalmic solution for ocular (topical) use. It treats postoperative ocular inflammation and ocular pain after surgery.

GNH USA supplies Ketorolac Micro Labs as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Ketorolac Trometamol is an NSAID used to manage inflammation and pain in the eye.

- Postoperative ocular inflammation: reduces swelling, redness and cellular infiltrate after eye surgery. - Ocular pain after surgery: provides analgesia to alleviate discomfort following ocular procedures. - Inflammatory ocular conditions: mitigates the inflammatory response in various eye disorders where topical NSAID therapy is appropriate.

Ketorolac ophthalmic solution may cause local ocular reactions and, rarely, severe systemic or ocular events.

Common Side Effects: - Burning or stinging sensation upon instillation. - Transient blurred vision. - Foreign body sensation. - Mild conjunctival hyperemia. - Increased tearing. - Temporary eyelid edema.

Serious or Rare Side Effects: - Severe allergic reaction (anaphylaxis) with swelling of the eyelids or face. - Corneal ulceration or epithelial defect. - Persistent intra‑ocular inflammation. - Stevens‑Johnson syndrome or toxic epidermal necrolysis involving the eye. - Significant vision loss. - Severe ocular pain unresponsive to therapy.

Before using Ketorolac ophthalmic solution, consider the following safety measures.

- NSAID hypersensitivity: avoid if the patient has known allergy to ketorolac or other NSAIDs. - Corneal disease: do not use in patients with active corneal ulceration or epithelial defects. - Intra‑ocular pressure: monitor IOP in patients with glaucoma or ocular hypertension. - Cardiovascular risk: use cautiously in patients with a history of cardiovascular disease or thromboembolic disorders. - Concurrent ocular NSAIDs: avoid simultaneous use of other topical NSAIDs to reduce additive toxicity. - Store at room temperature: keep in the original container, protect from light and moisture, and do not freeze.

Ketorolac ophthalmic solution can interact with systemic and ocular medications; awareness helps minimize adverse outcomes.

Major Interactions (Avoid): - Systemic NSAIDs (e.g., ibuprofen, naproxen): increased risk of bleeding and additive renal effects. - Anticoagulants (e.g., warfarin, direct oral anticoagulants): heightened potential for ocular hemorrhage. - Corticosteroid eye drops: may diminish anti‑inflammatory efficacy when used concurrently.

Moderate Interactions (Monitor Closely): - Beta‑blocker eye drops: possible alteration of intra‑ocular pressure control. - Diuretics (e.g., furosemide): monitor renal function if systemic exposure is significant. - ACE inhibitors or ARBs: observe for any changes in blood pressure or renal parameters when systemic NSAID absorption occurs.