Ketorolac Accord (Ketorolac Trometamol)

Ketorolac Trometamol, the active ingredient in Ketorolac Accord, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It provides short‑term management of moderate to severe pain, including post‑operative pain, in adult patients.

GNH USA supplies Ketorolac Accord as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ketorolac Accord is an NSAID used for acute pain conditions where rapid analgesia is required.

- Moderate to severe acute pain: delivers effective short‑term analgesia for up to five days. - Post‑operative pain: reduces pain intensity after surgical procedures. - Dental pain: alleviates pain following dental extractions or surgery.

Ketorolac may cause a range of adverse reactions, from mild to severe.

Common Side Effects: - Gastrointestinal discomfort or dyspepsia. - Nausea and vomiting. - Headache. - Dizziness or vertigo. - Mild renal function changes. - Elevated blood pressure.

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulceration. - Severe renal failure. - Anaphylactic or severe allergic reactions. - Cardiovascular events such as myocardial infarction. - Hepatic dysfunction. - Thrombocytopenia or other hematologic abnormalities.

When prescribing Ketorolac Accord, clinicians should consider several safety measures.

- Assess renal function: avoid or adjust dose in patients with severe renal impairment. - Monitor gastrointestinal risk: use cautiously in individuals with a history of ulcers or bleeding. - Check for hypersensitivity: contraindicated in patients with known NSAID allergy. - Limit duration: therapy should not exceed five days for most indications. - Evaluate bleeding risk: exercise caution when combined with anticoagulants or antiplatelet agents. - Store at ambient temperature: keep in the original container, protect from moisture and light.

Ketorolac can interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of serious bleeding. - Concurrent NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity. - Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding tendency.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: may reduce renal perfusion, especially in volume‑depleted patients. - Diuretics: combined use can impair renal function. - Lithium: ketorolac may raise lithium serum concentrations, requiring monitoring.