GNH USA

Europe — EMA

Ketoprofeno Dompe

GNH USA supplies Ketoprofeno Dompe (Ketoprofen), a nonsteroidal anti-inflammatory drug for mild to moderate pain, rheumatoid arthritis and osteoarthritis.

Ketoprofen Lysine

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What is Ketoprofen Lysine?

Ketoprofen, the active ingredient in Ketoprofeno Dompe, is a nonsteroidal anti-inflammatory drug presented as an oral tablet for systemic use. It is used to relieve mild to moderate pain and inflammation associated with conditions such as rheumatoid arthritis, osteoarthritis and musculoskeletal injuries.

GNH USA supplies Ketoprofeno Dompe as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Ketoprofen Lysine used for?

Ketoprofeno Dompe, an NSAID, is indicated for inflammatory and painful musculoskeletal conditions. - Rheumatoid arthritis: reduces joint inflammation and pain, improving mobility. - Osteoarthritis: alleviates chronic joint pain and helps maintain function. - Musculoskeletal pain: provides analgesic relief for strains, sprains and other soft‑tissue injuries.

What are the side effects of Ketoprofen Lysine?

Ketoprofeno Dompe may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects: - Gastrointestinal discomfort, such as dyspepsia or nausea. - Headache or dizziness. - Mild skin rash or itching. - Elevated blood pressure. - Fluid retention or peripheral edema. - Transient increase in liver enzymes.

Serious or Rare Side Effects: - Gastrointestinal ulceration or bleeding. - Severe renal impairment or acute kidney injury. - Anaphylactic or severe hypersensitivity reactions. - Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Hepatotoxicity with jaundice. - Cardiovascular events such as myocardial infarction or stroke.

What precautions apply to Ketoprofen Lysine?

Before initiating therapy with Ketoprofeno Dompe, consider the following safety measures. - Assess renal function: avoid use in severe renal impairment. - Monitor hepatic function: discontinue if significant liver enzyme elevation occurs. - Avoid in patients with known hypersensitivity to ketoprofen or other NSAIDs. - Use caution when combined with anticoagulants or antiplatelet agents due to bleeding risk. - Limit duration in elderly patients because of increased gastrointestinal complications. - Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

What does Ketoprofen Lysine interact with?

Ketoprofeno Dompe can interact with several drug classes; some combinations should be avoided while others require close monitoring.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): heightened risk of serious bleeding. - Selective COX‑2 inhibitors (e.g., celecoxib): additive gastrointestinal and cardiovascular toxicity. - High‑dose aspirin: increased gastrointestinal ulcer risk.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: possible decline in renal function, especially in volume‑depleted patients. - Loop or thiazide diuretics: may reduce diuretic efficacy and increase nephrotoxicity. - Lithium: ketoprofen can raise serum lithium levels, necessitating monitoring.

Frequently asked questions

What conditions is Ketoprofeno Dompe used to treat?+
Ketoprofeno Dompe contains ketoprofen lysine, an NSAID that is commonly prescribed for mild to moderate pain, inflammatory joint diseases such as rheumatoid arthritis and osteoarthritis, and acute musculoskeletal pain caused by strains, sprains or other soft‑tissue injuries.
How does ketoprofen work to relieve pain and inflammation?+
Ketoprofen inhibits the cyclooxygenase enzymes COX‑1 and COX‑2, which are essential for converting arachidonic acid into prostaglandins. By reducing prostaglandin production, the drug diminishes inflammation, lowers pain‑signal transmission, and helps control fever.
What is the usual dose of Ketoprofeno Dompe?+
The specific dose of Ketoprofeno Dompe is determined by the prescribing healthcare professional based on the patient’s condition, age, renal and hepatic function, and other individual factors. Patients should follow the prescriber’s instructions and not adjust the dose on their own.
Is Ketoprofeno Dompe safe to use during pregnancy or breastfeeding?+
Safety of ketoprofen in pregnancy and lactation has not been definitively established. It is generally advised to avoid NSAIDs, including ketoprofen, during the third trimester and to discuss potential risks with a healthcare provider before use in pregnancy or while nursing.
How do I order Ketoprofeno Dompe from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Ketoprofeno Dompe compare with other NSAIDs?+
Ketoprofen is similar to other non‑selective NSAIDs such as ibuprofen and naproxen in its mechanism of COX inhibition, but it may offer a slightly longer duration of analgesia for some patients. Choice of NSAID depends on individual response, safety profile, and physician preference.
What are the recommended storage conditions for Ketoprofeno Dompe?+
Ketoprofeno Dompe should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original packaging, protect them from moisture, heat and direct sunlight to maintain stability.
How is Ketoprofeno Dompe administered?+
The medication is taken orally, usually with a full glass of water. It can be taken with or without food, although taking it with food may reduce the likelihood of gastrointestinal discomfort.
What are the most serious risks associated with Ketoprofeno Dompe?+
Serious risks include gastrointestinal bleeding or ulceration, severe renal impairment, hepatotoxicity, and rare but life‑threatening hypersensitivity reactions such as Stevens‑Johnson syndrome or anaphylaxis. Patients should seek immediate medical attention if they experience signs of these conditions.
Who should not use Ketoprofeno Dompe?+
Ketoprofeno Dompe should be avoided in individuals with known hypersensitivity to ketoprofen or other NSAIDs, those with active peptic ulcer disease, severe renal or hepatic impairment, and patients who are in the third trimester of pregnancy. Consultation with a healthcare professional is essential before starting therapy.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Ketoprofen Lysine
Route
Oral Use
Manufacturer
Dompé Farmaceutici S.P.A.
Origin
EU

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