Ketoprofene Lp Arrow

Ketoprofen, the active ingredient in Ketoprofene Lp Arrow, is a nonsteroidal anti‑inflammatory drug (NSAID) presented as an oral tablet for oral use. It is employed to relieve mild to moderate pain and to reduce inflammation associated with conditions such as rheumatoid arthritis, osteoarthritis and other musculoskeletal disorders, primarily in adult patients. The drug works by inhibiting cyclooxygenase enzymes, which lowers prostaglandin production and thereby diminishes the inflammatory response. It is formulated for systemic absorption after swallowing and is intended for short‑term management under medical supervision.

GNH USA supplies Ketoprofene Lp Arrow as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ketoprofen is indicated for inflammatory and pain‑related conditions that involve the cyclooxygenase pathway. - Rheumatoid arthritis: reduces joint inflammation and pain, improving mobility. - Osteoarthritis: alleviates chronic joint discomfort and swelling. - Musculoskeletal pain: provides analgesic relief for strains, sprains and back pain. - Mild to moderate acute pain: manages postoperative or injury‑related pain where NSAID therapy is appropriate.

Ketoprofen may cause a range of adverse reactions, which are generally categorized by frequency and severity.

Common Side Effects: - Gastrointestinal discomfort: nausea, dyspepsia or abdominal pain. - Headache: mild to moderate intensity. - Dizziness or vertigo. - Skin rash or pruritus. - Diarrhea: loose stools occasionally. - Peripheral edema: mild swelling of lower limbs.

Serious or Rare Side Effects: - Peptic ulcer disease or gastrointestinal bleeding. - Severe hepatic injury or markedly elevated liver enzymes. - Renal impairment or acute kidney injury. - Anaphylactic or severe hypersensitivity reactions. - Myocardial infarction or other thrombotic cardiovascular events.

When prescribing or dispensing ketoprofen, several safety considerations should be observed to minimize risk. - Assess gastrointestinal risk: avoid in patients with active ulcers or a history of GI bleeding. - Evaluate renal function: use caution in those with impaired kidney function or dehydration. - Monitor hepatic status: avoid in severe liver disease and check liver enzymes periodically. - Cardiovascular caution: consider risk of thrombotic events in patients with established heart disease. - Concomitant drug review: avoid concurrent use with other NSAIDs, anticoagulants or corticosteroids without supervision. - Store at ambient temperature: keep below 25 °C in the original packaging, protected from moisture and light.

Ketoprofen can interact with several medicines, altering efficacy or increasing toxicity.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): heightened bleeding risk. - Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity. - SSRIs or SNRIs: increased chance of GI bleeding.

Moderate Interactions (Monitor Closely): - Lithium: NSAIDs can raise lithium serum levels. - Methotrexate: reduced clearance leading to toxicity. - Corticosteroids: enhanced risk of ulceration.