GNH USA

Europe — EMA

Ketoprofen Tis

GNH USA supplies Ketoprofen Tis (Ketoprofen), a nonsteroidal anti-inflammatory drug for relief of mild to moderate pain and reduction of inflammation.

Ketoprofen

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What is Ketoprofen?

Ketoprofen, the active ingredient in Ketoprofen Tis, is a nonsteroidal anti-inflammatory drug presented as a topical formulation for external use. It relieves mild to moderate pain and reduces inflammation in musculoskeletal conditions, providing local analgesia without systemic exposure. GNH USA supplies Ketoprofen Tis as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Ketoprofen used for?

Ketoprofen Tis is a topical NSAID that acts on inflammatory pathways to alleviate pain and swelling in several musculoskeletal disorders. - Musculoskeletal pain: reduces localized pain and inflammation. - Osteoarthritis: alleviates joint discomfort and stiffness. - Tendinitis: decreases swelling and tenderness. - Post‑traumatic soft‑tissue injury: provides local analgesia. - Rheumatoid arthritis (adjunct): helps control localized joint inflammation.

What are the side effects of Ketoprofen?

Ketoprofen Tis may cause local and, rarely, systemic adverse reactions.

Common Side Effects: - Skin irritation: mild redness or discomfort at the application site. - Itching: localized pruritus. - Dryness: transient dryness of the treated skin. - Burning sensation: brief warmth or burning feeling.

Serious or Rare Side Effects: - Allergic contact dermatitis: severe rash or swelling. - Stevens‑Johnson syndrome: rare but life‑threatening skin reaction. - Systemic NSAID toxicity: such as gastrointestinal ulceration, though uncommon with topical use. - Anaphylaxis: acute allergic response requiring emergency care. - Hepatotoxicity: rare liver injury with extensive use.

What precautions apply to Ketoprofen?

Before using Ketoprofen Tis, consider the following safety measures. - NSAID allergy: avoid if the patient has known hypersensitivity to ketoprofen or other NSAIDs. - Skin integrity: do not apply to broken, infected, or irritated skin. - Cardiovascular risk: use cautiously in patients with heart disease or hypertension. - Renal function: limit duration in individuals with renal impairment. - Pregnancy and lactation: only if benefits outweigh potential risks. - Store at room temperature: keep in the original container, protect from moisture and light.

What does Ketoprofen interact with?

Ketoprofen Tis can interact with other medicines; some combinations should be avoided while others require monitoring.

Major Interactions (Avoid): - Oral NSAIDs: increased systemic exposure and gastrointestinal risk. - Anticoagulants (e.g., warfarin): heightened bleeding tendency. - Lithium: potential elevation of lithium serum levels.

Moderate Interactions (Monitor Closely): - Corticosteroids: additive skin thinning and irritation. - SSRIs: may increase risk of bleeding when combined with topical NSAID.

Frequently asked questions

What is Ketoprofen Tis used for?+
Ketoprofen Tis is a topical formulation of the NSAID ketoprofen. It is used to relieve mild to moderate pain and to reduce inflammation associated with musculoskeletal conditions such as osteoarthritis, tendinitis, and soft‑tissue injuries.
How does ketoprofen work in Ketoprofen Tis?+
Ketoprofen inhibits the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes in the skin and underlying tissues. By blocking these enzymes, it lowers prostaglandin production, which diminishes inflammation, pain signalling, and swelling at the site where the gel is applied.
What is the usual dose of Ketoprofen Tis?+
The appropriate dose and frequency of Ketoprofen Tis are determined by the prescribing healthcare professional based on the patient’s condition, severity of symptoms, and treatment guidelines. Patients should follow the prescriber’s instructions and the product label.
Is Ketoprofen Tis safe during pregnancy or breastfeeding?+
Safety of topical ketoprofen in pregnancy or lactation has not been definitively established. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.
How do I order Ketoprofen Tis from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.
How does Ketoprofen Tis compare with other topical NSAIDs?+
Ketoprofen Tis offers a potent COX‑1/COX‑2 inhibition profile similar to other topical NSAIDs such as diclofenac gel. Its relatively high skin penetration can provide rapid pain relief, but individual response and tolerability may vary, so clinicians choose the product based on patient history and therapeutic goals.
What are the storage and handling requirements for Ketoprofen Tis?+
Ketoprofen Tis should be stored at room temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture and direct sunlight, and keep it out of reach of children.
How is Ketoprofen Tis applied?+
The gel is applied to clean, dry skin over the affected area. A thin layer is spread gently and massaged until absorbed, typically 2–4 times daily or as directed by the prescriber. Hands should be washed after application to avoid accidental contact with eyes or mucous membranes.
What are the most serious risks associated with Ketoprofen Tis?+
Serious risks, though rare, include severe allergic reactions such as Stevens‑Johnson syndrome, anaphylaxis, and systemic NSAID toxicity like gastrointestinal ulceration. Patients should discontinue use and seek immediate medical attention if they experience widespread rash, blistering, or signs of an allergic reaction.
Who should not use Ketoprofen Tis?+
Ketoprofen Tis should not be used by individuals with known hypersensitivity to ketoprofen or other NSAIDs, those with active skin infections at the application site, or patients with severe cardiovascular, renal, or hepatic disease unless specifically advised by a healthcare professional.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Ketoprofen
Route
Cutaneous Use
Manufacturer
Tis Farmaceutic Sa
Origin
EU

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